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AP2M1 adaptor related protein complex 2 mu 1 subunit [ Gallus gallus (chicken) ]

Gene ID: 770246, updated on 17-Aug-2024

Summary

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Symbol
AP2M1provided by CGNC
Full Name
adaptor related protein complex 2 mu 1 subunitprovided by CGNC
Primary source
CGNC:6392
See related
Ensembl:ENSGALG00010019023
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See AP2M1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 9 NC_052540.1 (15516699..15539370)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 9 NC_052581.1 (15310500..15333188)

Chromosome 9 - NC_052540.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2B subunit epsilon Neighboring gene dishevelled segment polarity protein 2 Neighboring gene PHD finger protein 13-like Neighboring gene ATP binding cassette subfamily F member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables clathrin adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in clathrin-dependent endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of AP-2 adaptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
AP-2 complex subunit mu
Names
AP-2 complex subunit mu-1
AP-2 mu chain
AP-2 mu-2 chain
HA2 50 kDa subunit
clathrin assembly protein complex 2 medium chain
clathrin assembly protein complex 2 mu medium chain
clathrin coat assembly protein AP50
clathrin coat-associated protein AP50
mu2-adaptin
plasma membrane adaptor AP-2 50 kDa protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079494.2 → NP_001072962.1  AP-2 complex subunit mu isoform 1

    See identical proteins and their annotated locations for NP_001072962.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000240
    UniProtKB/Swiss-Prot
    Q5ZMP6
    Related
    ENSGALP00010027460.1, ENSGALT00010046066.1
    Conserved Domains (2) summary
    cd09251
    Location:166 → 432
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 140
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

  2. NM_001396235.1 → NP_001383164.1  AP-2 complex subunit mu isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000240
    UniProtKB/TrEMBL
    A0A8V0Z9Y8
    Related
    ENSGALP00010027454.1, ENSGALT00010046060.1
    Conserved Domains (2) summary
    cd09251
    Location:168 → 434
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 140
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

  3. NM_001396236.1 → NP_001383165.1  AP-2 complex subunit mu isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000240
    UniProtKB/Swiss-Prot
    Q5ZMP6
    Conserved Domains (2) summary
    cd09251
    Location:166 → 432
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 140
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    15516699..15539370
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040705625.2 → XP_040561559.1  AP-2 complex subunit mu isoform X1

    Conserved Domains (2) summary
    cd09251
    Location:170 → 440
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 142
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

  2. XM_040705628.2 → XP_040561562.1  AP-2 complex subunit mu isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZFX8
    Conserved Domains (2) summary
    cd09251
    Location:168 → 438
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 140
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

  3. XM_040705630.2 → XP_040561564.1  AP-2 complex subunit mu isoform X5

    Conserved Domains (2) summary
    cd09251
    Location:166 → 436
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 140
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

  4. XM_046898480.1 → XP_046754436.1  AP-2 complex subunit mu isoform X1

  5. XM_040705624.2 → XP_040561558.1  AP-2 complex subunit mu isoform X1

    Conserved Domains (2) summary
    cd09251
    Location:170 → 440
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 142
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

  6. XM_015291442.4 → XP_015146928.1  AP-2 complex subunit mu isoform X4

    Conserved Domains (2) summary
    cd09251
    Location:170 → 436
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 142
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

  7. XM_040705627.2 → XP_040561561.1  AP-2 complex subunit mu isoform X3

    Conserved Domains (2) summary
    cd09251
    Location:168 → 438
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 142
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

  8. XM_015291446.4 → XP_015146932.1  AP-2 complex subunit mu isoform X6

    Conserved Domains (2) summary
    cd09251
    Location:168 → 434
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 142
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

  9. XM_040705626.2 → XP_040561560.1  AP-2 complex subunit mu isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZFX8
    Related
    ENSGALP00010027463.1, ENSGALT00010046069.1
    Conserved Domains (2) summary
    cd09251
    Location:168 → 438
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 140
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

  10. XM_040705629.2 → XP_040561563.1  AP-2 complex subunit mu isoform X5

    Conserved Domains (2) summary
    cd09251
    Location:166 → 436
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
    cd14836
    Location:1 → 140
    AP2_Mu_N; AP-2 complex subunit mu N-terminal domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    15310500..15333188
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046924013.1 → XP_046779969.1  AP-2 complex subunit mu isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZFX8

  2. XM_046924018.1 → XP_046779974.1  AP-2 complex subunit mu isoform X7

    UniProtKB/Swiss-Prot
    Q5ZMP6

  3. XM_046924009.1 → XP_046779965.1  AP-2 complex subunit mu isoform X1

  4. XM_046924008.1 → XP_046779964.1  AP-2 complex subunit mu isoform X1

  5. XM_046924007.1 → XP_046779963.1  AP-2 complex subunit mu isoform X1

  6. XM_046924012.1 → XP_046779968.1  AP-2 complex subunit mu isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZFX8

  7. XM_046924016.1 → XP_046779972.1  AP-2 complex subunit mu isoform X5

  8. XM_046924006.1 → XP_046779962.1  AP-2 complex subunit mu isoform X1

  9. XM_046924014.1 → XP_046779970.1  AP-2 complex subunit mu isoform X4

  10. XM_046924011.1 → XP_046779967.1  AP-2 complex subunit mu isoform X3

  11. XM_046924017.1 → XP_046779973.1  AP-2 complex subunit mu isoform X6

  12. XM_046924010.1 → XP_046779966.1  AP-2 complex subunit mu isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZFX8

  13. XM_046924015.1 → XP_046779971.1  AP-2 complex subunit mu isoform X5

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5ZMP6.1 GenPept UniProtKB/Swiss-Prot:Q5ZMP6

Gene LinkOut

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