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USP48 ubiquitin specific peptidase 48 [ Gallus gallus (chicken) ]

Gene ID: 769457, updated on 17-Aug-2024

Summary

Official Symbol
USP48provided by CGNC
Official Full Name
ubiquitin specific peptidase 48provided by CGNC
Primary source
CGNC:10544
See related
Ensembl:ENSGALG00010018251
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
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Genomic context

See USP48 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
28
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (6552494..6576987)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (6587504..6611985)

Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene chymotrypsin like elastase family member 3B Neighboring gene heparan sulfate proteoglycan 2 Neighboring gene RAP1 GTPase activating protein 1 Neighboring gene alkaline phosphatase, biomineralization associated

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
ubiquitin carboxyl-terminal hydrolase 48
Names
deubiquitinating enzyme 48
ubiquitin thioesterase 48
ubiquitin thiolesterase 48
ubiquitin-specific-processing protease 48
NP_001073211.2
XP_015152743.1
XP_024998322.1
XP_046759134.1
XP_046759135.1
XP_046759136.1
XP_046759137.1
XP_046787322.1
XP_046787323.1
XP_046787324.1
XP_046787325.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079743.2NP_001073211.2  ubiquitin carboxyl-terminal hydrolase 48

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000329
    UniProtKB/Swiss-Prot
    Q5ZM45
    UniProtKB/TrEMBL
    A0A1D5P1U8
    Related
    ENSGALP00010026196.1, ENSGALT00010044072.1
    Conserved Domains (3) summary
    cd02668
    Location:90417
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cd01795
    Location:9371032
    Ubl_USP48; ubiquitin-like (Ubl) domain found in ubiquitin-specific-processing protease 48 (USP48) and similar proteins
    cl12116
    Location:477554
    DUSP; DUSP domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    6552494..6576987
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025142554.3XP_024998322.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X3

    UniProtKB/Swiss-Prot
    Q5ZM45
    Conserved Domains (3) summary
    cd02668
    Location:90417
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam06337
    Location:481552
    DUSP; DUSP domain
    cl00155
    Location:9271027
    UBQ; Ubiquitin-like proteins
  2. XM_046903179.1XP_046759135.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X2

    UniProtKB/Swiss-Prot
    Q5ZM45
    UniProtKB/TrEMBL
    A0A1D5P1U8
    Related
    ENSGALP00010026204.1, ENSGALT00010044085.1
  3. XM_046903181.1XP_046759137.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X5

    UniProtKB/Swiss-Prot
    Q5ZM45
  4. XM_015297257.4XP_015152743.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X6

    UniProtKB/TrEMBL
    A0A8V0YYT7
    Related
    ENSGALP00010026199.1, ENSGALT00010044077.1
    Conserved Domains (4) summary
    cd02668
    Location:90417
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam00443
    Location:89416
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam06337
    Location:481552
    DUSP; DUSP domain
    cl00155
    Location:892998
    UBQ; Ubiquitin-like proteins
  5. XM_046903180.1XP_046759136.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X4

    UniProtKB/TrEMBL
    A0A8V0Z6J8
  6. XM_046903178.1XP_046759134.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z6J8
    Related
    ENSGALP00010026192.1, ENSGALT00010044065.1

RNA

  1. XR_005841379.2 RNA Sequence

  2. XR_001469818.4 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    6587504..6611985
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046931367.1XP_046787323.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X3

    UniProtKB/Swiss-Prot
    Q5ZM45
  2. XM_046931366.1XP_046787322.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X2

    UniProtKB/Swiss-Prot
    Q5ZM45
    UniProtKB/TrEMBL
    A0A1D5P1U8
  3. XM_046931368.1XP_046787324.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X5

    UniProtKB/Swiss-Prot
    Q5ZM45
  4. XM_046931369.1XP_046787325.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X6

    UniProtKB/TrEMBL
    A0A8V0YYT7

RNA

  1. XR_006936862.1 RNA Sequence

  2. XR_006936863.1 RNA Sequence