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HAR1B highly accelerated region 1B [ Homo sapiens (human) ]

Gene ID: 768097, updated on 17-Sep-2024

Summary

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Official Symbol
HAR1Bprovided by HGNC
Official Full Name
highly accelerated region 1Bprovided by HGNC
Primary source
HGNC:HGNC:33118
See related
Ensembl:ENSG00000231133 MIM:610557; AllianceGenome:HGNC:33118
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HAR1R; LINC00065; NCRNA00065
Expression
Biased expression in testis (RPKM 2.6), brain (RPKM 0.9) and 6 other tissues See more
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Genomic context

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See HAR1B in Genome Data Viewer
Location:
20q13.33
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (63095493..63102319, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (64897543..64904921, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (61726845..61733671, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1056 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:61687794-61687994 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61690954-61691796 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61691797-61692638 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:61699516-61700022 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61700597-61701098 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61701099-61701598 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18224 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13145 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61704121-61704620 Neighboring gene long intergenic non-protein coding RNA 1749 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13146 Neighboring gene highly accelerated region 1A Neighboring gene uncharacterized LOC105372719 Neighboring gene MPRA-validated peak4307 silencer Neighboring gene ReSE screen-validated silencer GRCh37_chr20:61751164-61751347 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61753175-61753676 Neighboring gene uncharacterized LOC105376996

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. The expression profile of HAR1A and HAR1B in the peripheral blood cells of multiple sclerosis patients. Akbarzadeh S, et al. Mol Biol Rep, 2023 Mar. PMID 36583781
  2. Expression profiling of cancer-related long non-coding RNAs revealed upregulation and biomarker potential of HAR1B and JPX in colorectal cancer. Khajehdehi M, et al. Mol Biol Rep, 2022 Jul. PMID 35526243
  3. An RNA gene expressed during cortical development evolved rapidly in humans. Pollard KS, et al. Nature, 2006 Sep 14. PMID 16915236
  4. lncRNAdb: a reference database for long noncoding RNAs. Amaral PP, et al. Nucleic Acids Res, 2011 Jan. PMID 21112873, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The expression profile of HAR1A and HAR1B in the peripheral blood cells of multiple sclerosis patients.
    Title: The expression profile of HAR1A and HAR1B in the peripheral blood cells of multiple sclerosis patients.
  2. Expression profiling of cancer-related long non-coding RNAs revealed upregulation and biomarker potential of HAR1B and JPX in colorectal cancer.
    Title: Expression profiling of cancer-related long non-coding RNAs revealed upregulation and biomarker potential of HAR1B and JPX in colorectal cancer.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • highly accelerated region 1B (non-protein coding)
  • highly accelerated region 1B (non-protein-coding RNA)
  • human accelerated region 1, reverse
  • long intergenic non-protein coding RNA 65

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003245.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    DQ860410
    Related
    ENST00000447910.2

  2. NR_152601.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    DQ860411
    Related
    ENST00000608031.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    63095493..63102319 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    64897543..64904921 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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