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GRN granulin precursor [ Bos taurus (domestic cattle) ]

Gene ID: 767942, updated on 4-Oct-2024

Summary

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Official Symbol
GRNprovided by VGNC
Official Full Name
granulin precursorprovided by VGNC
Primary source
VGNC:VGNC:29663
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See GRN in Genome Data Viewer
Location:
chromosome: 19
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (44149159..44156199)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene RUN domain containing 3A Neighboring gene solute carrier family 25 member 39 Neighboring gene family with sequence similarity 171 member A2 Neighboring gene integrin subunit alpha 2b Neighboring gene uncharacterized LOC132343085

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC127568

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
granulins; progranulin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    44149159..44156199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010816405.4 → XP_010814707.2  progranulin

    UniProtKB/TrEMBL
    Q2HJI6
    Conserved Domains (2) summary
    smart00277
    Location:128 → 178
    GRAN; Granulin
    pfam00396
    Location:371 → 404
    Granulin

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001077014.1: Suppressed sequence

    Description
    NM_001077014.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from frog (X.tr): grn (GeneID:594884).
Nucleotide Protein Strain
Heading Accession and Version

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Molecular Biology Databases
Research Materials