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Dipk2b divergent protein kinase domain 2B [ Mus musculus (house mouse) ]

Gene ID: 75905, updated on 28-Oct-2024

Summary

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Official Symbol
Dipk2bprovided by MGI
Official Full Name
divergent protein kinase domain 2Bprovided by MGI
Primary source
MGI:MGI:1923155
See related
Ensembl:ENSMUSG00000037358 AllianceGenome:MGI:1923155
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930578C19Rik
Summary
Predicted to be located in extracellular region. Orthologous to human DIPK2B (divergent protein kinase domain 2B). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Broad expression in subcutaneous fat pad adult (RPKM 2.2), lung adult (RPKM 1.9) and 19 other tissues See more
Orthologs
human all
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Genomic context

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See Dipk2b in Genome Data Viewer
Location:
X A1.3; X 13.73 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (18280406..18327657, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (18414167..18461419, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_46842 Neighboring gene STARR-seq mESC enhancer starr_46843 Neighboring gene STARR-seq mESC enhancer starr_46844 Neighboring gene STARR-seq mESC enhancer starr_46845 Neighboring gene STARR-seq mESC enhancer starr_46846 Neighboring gene STARR-seq mESC enhancer starr_46847 Neighboring gene nuclear encoded rRNA 5S 5 Neighboring gene up-regulated during skeletal muscle growth protein 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_46848 Neighboring gene STARR-seq mESC enhancer starr_46849 Neighboring gene STARR-seq mESC enhancer starr_46850 Neighboring gene STARR-seq mESC enhancer starr_46853 Neighboring gene STARR-seq mESC enhancer starr_46854 Neighboring gene STARR-seq mESC enhancer starr_46855 Neighboring gene STARR-seq mESC enhancer starr_46856 Neighboring gene STARR-seq mESC enhancer starr_46857 Neighboring gene STARR-seq mESC enhancer starr_46859 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene microRNA 221

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
divergent protein kinase domain 2B
Names
UPF0672 protein CXorf36 homolog
deleted in autism-related protein 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175228.4 → NP_780437.1  divergent protein kinase domain 2B precursor

    See identical proteins and their annotated locations for NP_780437.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the protein-coding transcript.
    Source sequence(s)
    AK085770, AK163928
    Consensus CDS
    CCDS30038.1
    UniProtKB/Swiss-Prot
    Q8C3I9
    Related
    ENSMUSP00000046567.5, ENSMUST00000044188.5
    Conserved Domains (1) summary
    pfam12260
    Location:213 → 393
    PIP49_C; Protein-kinase domain of FAM69

RNA

  1. NR_132634.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains two alternate internal exons and two alternate exons at the 3' end compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK163928
    Related
    ENSMUST00000147039.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    18280406..18327657 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527709.4 → XP_006527772.1  divergent protein kinase domain 2B isoform X1

    See identical proteins and their annotated locations for XP_006527772.1

    UniProtKB/TrEMBL
    Q3TQ46
    Conserved Domains (1) summary
    pfam12260
    Location:13 → 193
    PIP49_C; Protein-kinase domain of FAM69

  2. XM_006527708.5 → XP_006527771.1  divergent protein kinase domain 2B isoform X1

    See identical proteins and their annotated locations for XP_006527771.1

    UniProtKB/TrEMBL
    Q3TQ46
    Conserved Domains (1) summary
    pfam12260
    Location:13 → 193
    PIP49_C; Protein-kinase domain of FAM69

RNA

  1. XR_386875.4 RNA Sequence

  2. XR_386876.4 RNA Sequence

  3. XR_878034.3 RNA Sequence

  4. XR_878033.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C3I9.1 GenPept UniProtKB/Swiss-Prot:Q8C3I9

Gene LinkOut

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