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Krt24 keratin 24 [ Mus musculus (house mouse) ]

Gene ID: 75706, updated on 2-Nov-2024

Summary

Official Symbol
Krt24provided by MGI
Official Full Name
keratin 24provided by MGI
Primary source
MGI:MGI:1922956
See related
Ensembl:ENSMUSG00000020913 AllianceGenome:MGI:1922956
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
K24; CK-24; 2310058N18Rik; 2310075C18Rik
Summary
Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Orthologous to human KRT24 (keratin 24). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Krt24 in Genome Data Viewer
Location:
11 D; 11 62.92 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (99170785..99176088, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (99279959..99285262, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 Neighboring gene STARR-seq mESC enhancer starr_30702 Neighboring gene keratin 222 Neighboring gene STARR-positive B cell enhancer ABC_E8451 Neighboring gene predicted gene, 32385 Neighboring gene STARR-seq mESC enhancer starr_30703 Neighboring gene keratin 25 Neighboring gene keratin 26

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in epithelial cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermediate filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
keratin, type I cytoskeletal 24
Names
cytokeratin-24
ortholog of keratin 24 KRT24
type I keratin-24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029393.2NP_083669.1  keratin, type I cytoskeletal 24

    See identical proteins and their annotated locations for NP_083669.1

    Status: VALIDATED

    Source sequence(s)
    AK010165, BC129847, BE947543
    Consensus CDS
    CCDS36305.1
    UniProtKB/Swiss-Prot
    A1L316, A1L317, Q8BKC6
    Related
    ENSMUSP00000017255.4, ENSMUST00000017255.4
    Conserved Domains (1) summary
    pfam00038
    Location:140450
    Filament; Intermediate filament protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    99170785..99176088 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)