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vapB toxin-antitoxin system antitoxin VapB [ Shigella boydii ]

Gene ID: 75204250, updated on 10-Oct-2024

Summary

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Gene symbol
vapB
Gene description
toxin-antitoxin system antitoxin VapB
Locus tag
CEH00_RS12465
Gene type
protein coding
Organism
Shigella boydii (strain: ESBL-W3-2, nat-host: Homo sapiens)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Old locus tag
CEH00_12515
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Genomic context

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NZ_NIYS01000082.1Genomic Context describing neighboring genes Neighboring gene outer membrane protein assembly factor BamC Neighboring gene phosphoribosylaminoimidazolesuccinocarboxamide synthase Neighboring gene type II toxin-antitoxin system VapC family toxin Neighboring gene neutral zinc metallopeptidase

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_NIYS01000082.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of the VapBC toxin-antitoxin complex from Shigella flexneri reveals a hetero-octameric DNA-binding assembly. Dienemann C, et al. J Mol Biol, 2011 Dec 16. PMID 22037005, Free PMC Article
  2. Plasmid maintenance functions of the large virulence plasmid of Shigella flexneri. Radnedge L, et al. J Bacteriol, 1997 Jun. PMID 9171415, Free PMC Article
  3. Ectopic production of VapCs from Enterobacteria inhibits translation and trans-activates YoeB mRNA interferase. Winther KS, et al. Mol Microbiol, 2009 May. PMID 19400780
  4. Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA. Winther KS, et al. Proc Natl Acad Sci U S A, 2011 May 3. PMID 21502523, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
toxin-antitoxin system antitoxin VapB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_NIYS01000082.1 Reference assembly

    Range
    32594..32821
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_000450524.1 MULTISPECIES: toxin-antitoxin system antitoxin VapB [Enterobacteriaceae]

    See identical proteins and their annotated locations for WP_000450524.1

    UniProtKB/TrEMBL
    A0A0E0XXE0, A0A2A2XLM4, A0A6H2GPA7, A0A7U9IX28, A0A7W3HYH3, A0A7Z1EMK1, A0A836NBS5, A0A8B3K500, A0A8E0FPV5, A0A8H9ADI6, A0A979H464, A0A9P2I9R1, A0AA35F782, A0AAD0K3B2, A0AAD2RZJ6, A0AAD2V3N1, A0AAD2YUC1, A0AAD2ZBQ3, A0AAN1S7F2, A0AAN3SFZ5, A0AAN3V4L6, A0AAN3Z395, A0AAP9SK93, A7ZPS0, E1J3E7, J7QU27, W1ET18
    Conserved Domains (1) summary
    COG4456
    Location:1 → 75
    VagC; Virulence-associated protein VagC (function unknown) [Function unknown]
Nucleotide Protein
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