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hspa12a heat shock protein 12A [ Danio rerio (zebrafish) ]

Gene ID: 751725, updated on 12-Sep-2024

Summary

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Official Symbol
hspa12aprovided by ZNC
Official Full Name
heat shock protein 12Aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-031001-1
See related
Ensembl:ENSDARG00000070603 AllianceGenome:ZFIN:ZDB-GENE-031001-1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:153612
Summary
Orthologous to human HSPA12A (heat shock protein family A (Hsp70) member 12A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See hspa12a in Genome Data Viewer
Location:
chromosome: 17
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (21220684..21280232, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (21201066..21260396, complement)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene phosphorylase, glycogen; brain Neighboring gene abhydrolase domain containing 12, lysophospholipase Neighboring gene enolase 4 Neighboring gene shootin 1 Neighboring gene ATPase, H+ transporting, lysosomal, V1 subunit B, member a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. p53 Protects Cells from Death at the Heatstroke Threshold Temperature. Gong L, et al. Cell Rep, 2019 Dec 10. PMID 31825845
  2. Comparative Study of the Molecular Characterization, Evolution, and Structure Modeling of Digestive Lipase Genes Reveals the Different Evolutionary Selection Between Mammals and Fishes. Tang SL, et al. Front Genet, 2022. PMID 35991544, Free PMC Article
  3. Shootins mediate collective cell migration and organogenesis of the zebrafish posterior lateral line system. Urasaki A, et al. Sci Rep, 2019 Aug 21. PMID 31434971, Free PMC Article
  4. Split top: a maternal cathepsin B that regulates dorsoventral patterning and morphogenesis. Langdon YG, et al. Development, 2016 Mar 15. PMID 26893345, Free PMC Article
  5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC153612

General protein information

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Preferred Names
heat shock 70 kDa protein 12A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001430854.1 → NP_001417783.1  heat shock 70 kDa protein 12A isoform 1

    Status: VALIDATED

    Source sequence(s)
    CU633972, CU634001, FQ377974
    UniProtKB/TrEMBL
    A0A2R8RN86, A0A8M6Z288
    Related
    ENSDARP00000149134.1, ENSDART00000181356.1

  2. NM_001430855.1 → NP_001417784.1  heat shock 70 kDa protein 12A isoform 2

    Status: VALIDATED

    Source sequence(s)
    CU633972, CU634001, FQ377974
    UniProtKB/TrEMBL
    A0A8M6YVN3, F1Q8K1
    Related
    ENSDARP00000106960.2, ENSDART00000123198.4

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    21220684..21280232 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017351677.3 → XP_017207166.1  heat shock 70 kDa protein 12A isoform X1

    UniProtKB/TrEMBL
    A0A8M6YT54

  2. XM_068214454.1 → XP_068070555.1  heat shock 70 kDa protein 12A isoform X2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001045435.1: Suppressed sequence

    Description
    NM_001045435.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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