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rpain RPA interacting protein [ Danio rerio (zebrafish) ]

Gene ID: 751671, updated on 2-Nov-2024

Summary

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Official Symbol
rpainprovided by ZNC
Official Full Name
RPA interacting proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060825-212
See related
Ensembl:ENSDARG00000063021 AllianceGenome:ZFIN:ZDB-GENE-060825-212
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:153251
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in protein import into nucleus. Predicted to be active in nucleus. Orthologous to human RPAIN (RPA interacting protein). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See rpain in Genome Data Viewer
Location:
chromosome: 5
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (3891530..3908849)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (3568037..3585396)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene serine/arginine repetitive matrix 3 Neighboring gene MLX interacting protein like Neighboring gene complement component 1, q subcomponent binding protein Neighboring gene zinc finger, HIT-type containing 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Rapid progression through the cell cycle ensures efficient migration of primordial germ cells - The role of Hsp90. Pfeiffer J, et al. Dev Biol, 2018 Apr 15. PMID 29477339
  2. Essential role of an ERV-derived Env38 protein in adaptive humoral immunity against an exogenous SVCV infection in a zebrafish model. Hong Y, et al. PLoS Pathog, 2023 Apr. PMID 37014912, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC153251

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RPA-interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045388.1 → NP_001038853.1  RPA-interacting protein

    See identical proteins and their annotated locations for NP_001038853.1

    Status: PROVISIONAL

    Source sequence(s)
    BC122206
    UniProtKB/TrEMBL
    Q0P498
    Related
    ENSDARP00000086144.4, ENSDART00000091711.6
    Conserved Domains (3) summary
    pfam14766
    Location:6 → 43
    RPA_interact_N; Replication protein A interacting N-terminal
    pfam14767
    Location:55 → 132
    RPA_interact_M; Replication protein A interacting middle
    pfam14768
    Location:143 → 223
    RPA_interact_C; Replication protein A interacting C-terminal

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    3891530..3908849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005171732.5 → XP_005171789.1  RPA-interacting protein isoform X1

    UniProtKB/TrEMBL
    A0A8M2BJ14, F1QKJ6
    Related
    ENSDARP00000108894.2, ENSDART00000129329.4
    Conserved Domains (3) summary
    pfam14766
    Location:6 → 43
    RPA_interact_N; Replication protein A interacting N-terminal
    pfam14767
    Location:55 → 132
    RPA_interact_M; Replication protein A interacting middle
    pfam14768
    Location:143 → 223
    RPA_interact_C; Replication protein A interacting C-terminal
Nucleotide Protein Strain
Heading Accession and Version

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