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Exoc3l2 exocyst complex component 3-like 2 [ Mus musculus (house mouse) ]

Gene ID: 74463, updated on 28-Oct-2024

Summary

Official Symbol
Exoc3l2provided by MGI
Official Full Name
exocyst complex component 3-like 2provided by MGI
Primary source
MGI:MGI:1921713
See related
Ensembl:ENSMUSG00000011263 AllianceGenome:MGI:1921713
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm19857; 4933417E01Rik
Summary
Predicted to enable SNARE binding activity. Acts upstream of or within in utero embryonic development. Predicted to be part of exocyst. Is expressed in rete testis and tunica albuginea of testis. Orthologous to human EXOC3L2 (exocyst complex component 3 like 2). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in adrenal adult (RPKM 22.7), kidney adult (RPKM 13.1) and 13 other tissues See more
Orthologs
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Genomic context

See Exoc3l2 in Genome Data Viewer
Location:
7 A3; 7 9.92 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (19197212..19230687)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (19463287..19496762)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene MAP/microtubule affinity regulating kinase 4 Neighboring gene STARR-positive B cell enhancer ABC_E8153 Neighboring gene predicted gene, 23099 Neighboring gene STARR-positive B cell enhancer ABC_E6520 Neighboring gene biogenesis of lysosomal organelles complex-1, subunit 3 Neighboring gene trafficking protein particle complex 6A

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in exocyst localization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of exocyst IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
exocyst complex component 3-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370800.1NP_001357729.1  exocyst complex component 3-like protein 2

    Status: VALIDATED

    Source sequence(s)
    AC149052
    Consensus CDS
    CCDS90173.1
    UniProtKB/TrEMBL
    D3YUP5
    Related
    ENSMUSP00000123025.3, ENSMUST00000137613.9
    Conserved Domains (1) summary
    cl19885
    Location:215742
    Sec6; Exocyst complex component Sec6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    19197212..19230687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_028954.2: Suppressed sequence

    Description
    NM_028954.2: This RefSeq was temporarily suppressed because the CDS was partial compared to orthologous protein data, and there was a deletion that resulted in a frameshifted coding region.