U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Slco6c1 solute carrier organic anion transporter family, member 6c1 [ Mus musculus (house mouse) ]

Gene ID: 74441, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Slco6c1provided by MGI
Official Full Name
solute carrier organic anion transporter family, member 6c1provided by MGI
Primary source
MGI:MGI:1921691
See related
Ensembl:ENSMUSG00000026331 AllianceGenome:MGI:1921691
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933404A18Rik
Summary
Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Part of CatSper complex. Orthologous to human SLCO6A1 (solute carrier organic anion transporter family member 6A1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward testis adult (RPKM 16.6) See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Slco6c1 in Genome Data Viewer
Location:
1 D; 1 47.76 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (96986763..97056066, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (97059038..97128339, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein F pseudogene Neighboring gene STARR-seq mESC enhancer starr_01773 Neighboring gene STARR-seq mESC enhancer starr_01774 Neighboring gene predicted gene 7133 Neighboring gene STARR-seq mESC enhancer starr_01775 Neighboring gene predicted gene 7135 Neighboring gene STARR-seq mESC enhancer starr_01776 Neighboring gene STARR-seq mESC enhancer starr_01777

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Structure of a mammalian sperm cation channel complex. Lin S, et al. Nature, 2021 Jul. PMID 34225353
  2. The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease. Willnow T, et al. Organogenesis, 2005 Apr. PMID 19521566, Free PMC Article
  3. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables organic anion transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables sodium-independent organic anion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within organic anion transport ISO
Inferred from Sequence Orthology
more info
  
involved_in organic anion transport ISO
Inferred from Sequence Orthology
more info
  
involved_in sodium-independent organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of CatSper complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
solute carrier organic anion transporter family member 6C1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028942.4 → NP_083218.1  solute carrier organic anion transporter family member 6C1

    See identical proteins and their annotated locations for NP_083218.1

    Status: PROVISIONAL

    Source sequence(s)
    AK029505
    Consensus CDS
    CCDS35677.1
    UniProtKB/Swiss-Prot
    Q3V161, Q8C0X7, Q9D4B7
    Related
    ENSMUSP00000027569.8, ENSMUST00000027569.14
    Conserved Domains (3) summary
    cd06174
    Location:97 → 463
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    cd01330
    Location:487 → 540
    KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
    pfam03137
    Location:95 → 654
    OATP; Organic Anion Transporter Polypeptide (OATP) family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    96986763..97056066 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529913.5 → XP_006529976.1  solute carrier organic anion transporter family member 6C1 isoform X1

    Conserved Domains (1) summary
    cl28910
    Location:93 → 544
    MFS; Major Facilitator Superfamily

  2. XM_006529914.3 → XP_006529977.1  solute carrier organic anion transporter family member 6C1 isoform X2

    Conserved Domains (1) summary
    cl28910
    Location:10 → 243
    MFS; Major Facilitator Superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C0X7.1 GenPept UniProtKB/Swiss-Prot:Q8C0X7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools