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Gcc1 golgi coiled coil 1 [ Mus musculus (house mouse) ]

Gene ID: 74375, updated on 28-Oct-2024

Summary

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Official Symbol
Gcc1provided by MGI
Official Full Name
golgi coiled coil 1provided by MGI
Primary source
MGI:MGI:1921625
See related
Ensembl:ENSMUSG00000029708 AllianceGenome:MGI:1921625
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4932417P04Rik
Summary
Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Orthologous to human GCC1 (GRIP and coiled-coil domain containing 1). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in testis adult (RPKM 4.9), colon adult (RPKM 3.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Gcc1 in Genome Data Viewer
Location:
6 A3.3; 6 11.99 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (28413784..28424152, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (28416603..28421724, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 6530409C15 gene Neighboring gene zinc finger protein 800 Neighboring gene STARR-seq mESC enhancer starr_15407 Neighboring gene STARR-seq mESC enhancer starr_15408 Neighboring gene kelch domain containing pseudogene Neighboring gene STARR-seq mESC enhancer starr_15409 Neighboring gene STARR-positive B cell enhancer mm9_chr6:28371614-28371915 Neighboring gene Pax4 5' regulatory region Neighboring gene ADP-ribosylation factor 5 Neighboring gene fascin actin-bundling protein 3 Neighboring gene paired box 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice. Fenske TS, et al. Cancer Res, 2006 May 15. PMID 16707424
  2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GRIP and coiled-coil domain-containing protein 1
Names
Golgi coiled coil protein 1
golgi coiled-coil protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427121.1 → NP_001414050.1  GRIP and coiled-coil domain-containing protein 1

    Status: VALIDATED

    Source sequence(s)
    AC068608
    UniProtKB/Swiss-Prot
    Q8CCR3, Q9D4H2
    Related
    ENSMUSP00000067395.7, ENSMUST00000064377.7

  2. NM_028900.5 → NP_083176.3  GRIP and coiled-coil domain-containing protein 1

    See identical proteins and their annotated locations for NP_083176.3

    Status: VALIDATED

    Source sequence(s)
    AC068608
    Consensus CDS
    CCDS19951.1
    UniProtKB/Swiss-Prot
    Q8CCR3, Q9D4H2
    Related
    ENSMUSP00000087997.4, ENSMUST00000090511.4
    Conserved Domains (2) summary
    pfam01465
    Location:721 → 763
    GRIP; GRIP domain
    cl19219
    Location:389 → 506
    DUF342; Protein of unknown function (DUF342)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    28413784..28424152 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D4H2.2 GenPept UniProtKB/Swiss-Prot:Q9D4H2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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