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Slc35a5 solute carrier family 35, member A5 [ Mus musculus (house mouse) ]

Gene ID: 74102, updated on 28-Oct-2024

Summary

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Official Symbol
Slc35a5provided by MGI
Official Full Name
solute carrier family 35, member A5provided by MGI
Primary source
MGI:MGI:1921352
See related
Ensembl:ENSMUSG00000022664 AllianceGenome:MGI:1921352
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D16Ertd450e; 1010001J06Rik; D730043G07Rik
Summary
Predicted to enable pyrimidine nucleotide-sugar transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in Golgi membrane. Is expressed in tail unsegmented mesenchyme and trunk somite. Orthologous to human SLC35A5 (solute carrier family 35 member A5). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in testis adult (RPKM 9.5), CNS E18 (RPKM 6.4) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Slc35a5 in Genome Data Viewer
Location:
16 B5; 16 29.44 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (44959936..44979036, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (45139573..45158673, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53958 Neighboring gene coiled-coil domain containing 80 Neighboring gene STARR-positive B cell enhancer ABC_E1490 Neighboring gene autophagy related 3 Neighboring gene STARR-positive B cell enhancer ABC_E1925 Neighboring gene 40S ribosomal protein S24-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Microarray analysis of somitogenesis reveals novel targets of different WNT signaling pathways in the somitic mesoderm. Buttitta L, et al. Dev Biol, 2003 Jun 1. PMID 12781685
  2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  3. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
  
enables pyrimidine nucleotide-sugar transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables pyrimidine nucleotide-sugar transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in pyrimidine nucleotide-sugar transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in Golgi membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
UDP-sugar transporter protein SLC35A5
Names
probable UDP-sugar transporter protein SLC35A5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356453.1 → NP_001343382.1  UDP-sugar transporter protein SLC35A5 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC129601
    Conserved Domains (1) summary
    pfam04142
    Location:43 → 386
    Nuc_sug_transp; Nucleotide-sugar transporter

  2. NM_028756.4 → NP_083032.2  UDP-sugar transporter protein SLC35A5 isoform 1

    See identical proteins and their annotated locations for NP_083032.2

    Status: VALIDATED

    Source sequence(s)
    AK003124, AK033921, CJ075331
    Consensus CDS
    CCDS28193.1
    UniProtKB/Swiss-Prot
    Q921R7, Q9DC72
    Related
    ENSMUSP00000023344.4, ENSMUST00000023344.10
    Conserved Domains (1) summary
    pfam04142
    Location:43 → 387
    Nuc_sug_transp; Nucleotide-sugar transporter

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    44959936..44979036 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522647.5 → XP_006522710.1  UDP-sugar transporter protein SLC35A5 isoform X1

    Conserved Domains (1) summary
    pfam04142
    Location:46 → 403
    Nuc_sug_transp; Nucleotide-sugar transporter

  2. XM_006522648.5 → XP_006522711.1  UDP-sugar transporter protein SLC35A5 isoform X2

    Conserved Domains (1) summary
    pfam04142
    Location:46 → 402
    Nuc_sug_transp; Nucleotide-sugar transporter

  3. XM_036160154.1 → XP_036016047.1  UDP-sugar transporter protein SLC35A5 isoform X3

    UniProtKB/Swiss-Prot
    Q921R7, Q9DC72
    Conserved Domains (1) summary
    pfam04142
    Location:43 → 387
    Nuc_sug_transp; Nucleotide-sugar transporter

  4. XM_036160155.1 → XP_036016048.1  UDP-sugar transporter protein SLC35A5 isoform X4

    Conserved Domains (1) summary
    pfam04142
    Location:43 → 386
    Nuc_sug_transp; Nucleotide-sugar transporter
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q921R7.3 GenPept UniProtKB/Swiss-Prot:Q921R7

Gene LinkOut

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