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CTSZ cathepsin Z [ Pan troglodytes (chimpanzee) ]

Gene ID: 736240, updated on 17-Aug-2024

Summary

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Official Symbol
CTSZprovided by VGNC
Official Full Name
cathepsin Zprovided by VGNC
Primary source
VGNC:VGNC:6087
Locus tag
CK820_G0037169
See related
Ensembl:ENSPTRG00000013679
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See CTSZ in Genome Data Viewer
Location:
chromosome: 21
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 21 NC_072419.2 (65291491..65303598, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 20 NC_072418.1 (65345908..65359077, complement)

Chromosome 21 - NC_072419.2Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 30-like Neighboring gene negative elongation factor complex member C/D Neighboring gene tubulin beta 1 class VI Neighboring gene ATP synthase F1 subunit epsilon

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cathepsin Z
XP_001140086.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072419.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    65291491..65303598 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001140086.6 → XP_001140086.1  cathepsin Z

    See identical proteins and their annotated locations for XP_001140086.1

    UniProtKB/TrEMBL
    A0A2J8KMP3, A0A6D2VSC6, H2QKN8, K7DSY9
    Related
    ENSPTRP00000023534.4
    Conserved Domains (1) summary
    cd02698
    Location:62 → 302
    Peptidase_C1A_CathepsinX; Cathepsin X; the only papain-like lysosomal cysteine peptidase exhibiting carboxymonopeptidase activity. It can also act as a carboxydipeptidase, like cathepsin B, but has been shown to preferentially cleave substrates through a monopeptidyl ...
Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials