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sp2.S Sp2 transcription factor S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 735230, updated on 4-Nov-2024

Summary

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Official Symbol
sp2.S
Official Full Name
Sp2 transcription factor S homeolog
Primary source
Xenbase:XB-GENE-968279
Locus tag
XELAEV_18045972mg
See related
EnsemblRapid:ENSXLAG00005023303 AllianceGenome:Xenbase:XB-GENE-968279
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
sp2
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Orthologous to human SP2 (Sp2 transcription factor). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sp2.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (2874808..2885855)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (2797097..2808243)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene secernin 2 S homeolog Neighboring gene Sp6 transcription factor S homeolog Neighboring gene uncharacterized XB5788060 S homeolog Neighboring gene pyridoxamine 5'-phosphate oxidase S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC132197

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sp2 transcription factor S homeolog; sp2 transcription factor S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096682.1 → NP_001090151.1  Sp2 transcription factor S homeolog

    See identical proteins and their annotated locations for NP_001090151.1

    Status: PROVISIONAL

    Source sequence(s)
    BC108817
    UniProtKB/TrEMBL
    A0A974BS97, Q32N61
    Conserved Domains (4) summary
    COG5048
    Location:466 → 535
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:477 → 496
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:472 → 496
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:518 → 543
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    2874808..2885855
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018237627.2 → XP_018093116.1  sp2 transcription factor S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J0TY62, A0A974BS97
    Related
    ENSXLAP00005068792.1, ENSXLAT00005070326.1

  2. XM_018237628.2 → XP_018093117.1  sp2 transcription factor S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J0TY62, A0A974BS97

  3. XM_041577875.1 → XP_041433809.1  sp2 transcription factor S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1LWQ6, A0A974BS97
    Conserved Domains (3) summary
    smart00355
    Location:558 → 580
    ZnF_C2H2; zinc finger
    COG5048
    Location:492 → 561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:503 → 522
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_041577876.1 → XP_041433810.1  sp2 transcription factor S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1LYK4, A0A974BS97
    Conserved Domains (3) summary
    smart00355
    Location:557 → 579
    ZnF_C2H2; zinc finger
    COG5048
    Location:491 → 560
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:502 → 521
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. XM_041577877.1 → XP_041433811.1  sp2 transcription factor S homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J1LXQ0, A0A974BS97
Nucleotide Protein Strain
Heading Accession and Version

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