fdps.L farnesyl diphosphate synthase L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: fdps.L
Official Full Name: farnesyl diphosphate synthase L homeolog
Primary source: Xenbase:XB-GENE-6254261
Locus tag: XELAEV_18040951mg
See related: EnsemblRapid:ENSXLAG00005003917 AllianceGenome:Xenbase:XB-GENE-6254261
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: fdps
Summary: Predicted to enable dimethylallyltranstransferase activity and geranyltranstransferase activity. Predicted to act upstream of or within farnesyl diphosphate biosynthetic process. Predicted to be located in cytoplasm and membrane. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human FDPS (farnesyl diphosphate synthase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 8L

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8L	NC_054385.1 (134892465..134897871, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8L	NC_030738.1 (119634186..119639826, complement)

Chromosome 8L - NC_054385.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables dimethylallyltranstransferase activity	IEA Inferred from Electronic Annotation more info
enables geranyltranstransferase activity	IEA Inferred from Electronic Annotation more info
enables prenyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within farnesyl diphosphate biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within isoprenoid biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: farnesyl diphosphate synthase L homeolog

Names: farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001096644.1 → NP_001090113.1 farnesyl diphosphate synthase L homeolog

See identical proteins and their annotated locations for NP_001090113.1

Status: PROVISIONAL

Source sequence(s)

BC106510

UniProtKB/TrEMBL

Q3KPW7

Related

ENSXLAP00005011713.1, ENSXLAT00005011887.1

Conserved Domains (1) summary

pfam00348
Location:45 → 305

polyprenyl_synt; Polyprenyl synthetase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

134892465..134897871 complement

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GenBank, FASTA, Sequence Viewer (Graphics)