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sgo1.L shugoshin 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 735145, updated on 4-Nov-2024

Summary

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Official Symbol
sgo1.L
Official Full Name
shugoshin 1 L homeolog
Primary source
Xenbase:XB-GENE-940797
Locus tag
XELAEV_18031038mg
See related
EnsemblRapid:ENSXLAG00005012754 AllianceGenome:Xenbase:XB-GENE-940797
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
sgo; sgo1; sgol1; sgol1.L
Summary
Predicted to act upstream of or within cell division and meiotic chromosome segregation. Predicted to be located in kinetochore; microtubule; and nucleus. Human ortholog(s) of this gene implicated in chronic atrial and intestinal dysrhythmia. Orthologous to human SGO1 (shugoshin 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sgo1.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (47276012..47294559, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (43491253..43510026, complement)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene RAB5A, member RAS oncogene family L homeolog Neighboring gene K(lysine) acetyltransferase 2B L homeolog Neighboring gene uncharacterized LOC121394587 Neighboring gene zinc finger protein 385D L homeolog Neighboring gene ubiquitin conjugating enzyme E2E 2 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis. Salic A, et al. Cell, 2004 Sep 3. PMID 15339662
  2. Shugoshin is a Mad1/Cdc20-like interactor of Mad2. Orth M, et al. EMBO J, 2011 Jun 10. PMID 21666598, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC115705

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chromosome segregation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within meiotic chromosome segregation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
shugoshin 1
Names
shugoshin-like 1 L homeolog
xsgo

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    47276012..47294559 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018266727.2 → XP_018122216.1  shugoshin 1

    UniProtKB/Swiss-Prot
    Q4KLP8
    UniProtKB/TrEMBL
    A0A974CP78
    Related
    ENSXLAP00005037531.1, ENSXLAT00005038441.1

  2. XM_018266728.2 → XP_018122217.1  shugoshin 1

    UniProtKB/Swiss-Prot
    Q4KLP8
    UniProtKB/TrEMBL
    A0A974CP78

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001096602.1: Suppressed sequence

    Description
    NM_001096602.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4KLP8.1 GenPept UniProtKB/Swiss-Prot:Q4KLP8

Gene LinkOut

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