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gas8.S growth arrest specific 8 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 735136, updated on 4-Nov-2024

Summary

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Official Symbol
gas8.S
Official Full Name
growth arrest specific 8 S homeolog
Primary source
Xenbase:XB-GENE-964840
Locus tag
XELAEV_18024885mg
See related
EnsemblRapid:ENSXLAG00005011046 AllianceGenome:Xenbase:XB-GENE-964840
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
gas8
Summary
Predicted to enable microtubule binding activity and small GTPase binding activity. Predicted to act upstream of or within flagellated sperm motility. Predicted to be located in Golgi apparatus; microtubule; and motile cilium. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 33. Orthologous to human GAS8 (growth arrest specific 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See gas8.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (41423275..41438754, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (40232175..40247654, complement)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121393239 Neighboring gene uncharacterized LOC108715416 Neighboring gene provisional ortholog of IST1 factor associated with ESCRT-III S homeolog Neighboring gene urate (5-hydroxyiso-) hydrolase S homeolog Neighboring gene dysbindin (dystrobrevin binding protein 1) domain containing 1 S homeolog Neighboring gene AFG3-like AAA ATPase 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC114774

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell motility IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within flagellated sperm motility IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
growth arrest specific 8 S homeolog
Names
growth arrest-specific 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096593.1 → NP_001090062.1  growth arrest specific 8 S homeolog

    See identical proteins and their annotated locations for NP_001090062.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098971
    UniProtKB/TrEMBL
    A0A974CYJ2, Q4KLW4
    Related
    ENSXLAP00005032484.1, ENSXLAT00005033274.1
    Conserved Domains (1) summary
    pfam13851
    Location:227 → 426
    GAS; Growth-arrest specific micro-tubule binding

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    41423275..41438754 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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