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clpx.L caseinolytic mitochondrial matrix peptidase chaperone subunit X L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 735100, updated on 4-Nov-2024

Summary

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Official Symbol
clpx.L
Official Full Name
caseinolytic mitochondrial matrix peptidase chaperone subunit X L homeolog
Primary source
Xenbase:XB-GENE-991459
Locus tag
XELAEV_18018424mg
See related
EnsemblRapid:ENSXLAG00005022489 AllianceGenome:Xenbase:XB-GENE-991459
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
EPP2; clpx
Summary
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and ATP-dependent protein folding chaperone. Predicted to act upstream of or within protein folding and proteolysis involved in protein catabolic process. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in erythropoietic protoporphyria. Orthologous to human CLPX (caseinolytic mitochondrial matrix peptidase chaperone subunit X). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See clpx.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (122650691..122694676)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (107237700..107281794)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and death domain containing 1A L homeolog Neighboring gene SPG21, maspardin L homeolog Neighboring gene programmed cell death 7 L homeolog Neighboring gene ubiquitin associated protein 1 like L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC114642

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent protein folding chaperone IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein folding IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
caseinolytic mitochondrial matrix peptidase chaperone subunit X L homeolog
Names
ClpX caseinolytic peptidase X homolog
caseinolytic mitochondrial matrix peptidase chaperone subunit L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096559.1 → NP_001090028.1  caseinolytic mitochondrial matrix peptidase chaperone subunit X L homeolog

    See identical proteins and their annotated locations for NP_001090028.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097522
    UniProtKB/TrEMBL
    A0A974DF92, Q4V866
    Related
    ENSXLAP00005066261.1, ENSXLAT00005067785.1
    Conserved Domains (2) summary
    PRK05342
    Location:163 → 599
    clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
    cl02609
    Location:95 → 123
    Zn-ribbon; C-terminal zinc ribbon domain of RNA polymerase intrinsic transcript cleavage subunit

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    122650691..122694676
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018251272.2 → XP_018106761.1  caseinolytic mitochondrial matrix peptidase chaperone subunit X L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J0UP05, A0A974DF92
    Related
    ENSXLAP00005066290.1, ENSXLAT00005067814.1
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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