vps35.S VPS35 retromer complex component S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: vps35.S
Official Full Name: VPS35 retromer complex component S homeolog
Primary source: Xenbase:XB-GENE-941157
Locus tag: XELAEV_18025036mg
See related: EnsemblRapid:ENSXLAG00005018346 AllianceGenome:Xenbase:XB-GENE-941157
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: mem3; vps35
Summary: Predicted to act upstream of or within intracellular protein transport and retrograde transport, endosome to Golgi. Predicted to be located in late endosome and membrane. Predicted to be part of retromer, cargo-selective complex. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 17. Orthologous to human VPS35 (VPS35 retromer complex component). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 4S

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4S	NC_054378.1 (57810178..57849111)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4S	NC_030731.1 (51624069..51663048)

Chromosome 4S - NC_054378.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Process	Evidence Code	Pubs
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within retrograde transport, endosome to Golgi	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in late endosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of retromer complex	IEA Inferred from Electronic Annotation more info
part_of retromer, cargo-selective complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: VPS35 retromer complex component S homeolog

Names: vacuolar protein sorting 35 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.