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ccno.S cyclin O S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734931, updated on 4-Nov-2024

Summary

Official Symbol
ccno.S
Official Full Name
cyclin O S homeolog
Primary source
Xenbase:XB-GENE-17332754
Locus tag
XELAEV_18010955mg
See related
EnsemblRapid:ENSXLAG00005005390 AllianceGenome:Xenbase:XB-GENE-17332754
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ccnu; udg2; ung2; ccno-b; cyclin-o
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Acts upstream of or within cilium assembly and multi-ciliated epithelial cell differentiation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 29. Orthologous to human CCNO (cyclin O). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See ccno.S in Genome Data Viewer
Location:
chromosome: 1S
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (180330551..180337079)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (160485556..160491945)

Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene MGC80748 protein Neighboring gene Mtr4 exosome RNA helicase S homeolog Neighboring gene uncharacterized LOC108707289 Neighboring gene multiciliate differentiation and DNA synthesis associated cell cycle protein S homeolog Neighboring gene glutathione peroxidase 8 (putative) S homeolog

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096396.1NP_001089865.1  cyclin-O protein B

    See identical proteins and their annotated locations for NP_001089865.1

    Status: PROVISIONAL

    Source sequence(s)
    BC108565
    UniProtKB/Swiss-Prot
    Q32NM1
    UniProtKB/TrEMBL
    A0A974DV77
    Related
    ENSXLAP00005015898.1, ENSXLAT00005016186.1
    Conserved Domains (2) summary
    pfam00134
    Location:118243
    Cyclin_N; Cyclin, N-terminal domain
    pfam02984
    Location:245349
    Cyclin_C; Cyclin, C-terminal domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    180330551..180337079
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018239670.2XP_018095159.1  cyclin-O protein B isoform X1

    UniProtKB/TrEMBL
    A0A8J0U2C3