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actn4.L actinin alpha 4 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734930, updated on 17-Aug-2024

Summary

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Official Symbol
actn4.L
Official Full Name
actinin alpha 4 L homeolog
Primary source
Xenbase:XB-GENE-17340657
Locus tag
XELAEV_18039391mg
See related
EnsemblRapid:ENSXLAG00005025132
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
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Genomic context

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Location:
chromosome: 8L
Exon count:
24
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (71930639..71972323, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (58442475..58484469, complement)

Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121397065 Neighboring gene lectin, galactoside-binding, soluble, 4, gene 2, L homeolog Neighboring gene calpain 12 L homeolog Neighboring gene provisional ortholog of inositol-tetrakisphosphate 1-kinase L homeolog Neighboring gene cilia- and flagella-associated protein 251

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC131041

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC734930

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096395.1 → NP_001089864.1  uncharacterized protein LOC734930

    See identical proteins and their annotated locations for NP_001089864.1

    Status: PREDICTED

    Source sequence(s)
    BC108564
    UniProtKB/TrEMBL
    Q32NM2
    Conserved Domains (3) summary
    cd00014
    Location:152 → 256
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00307
    Location:39 → 137
    CH; Calponin homology (CH) domain
    cl02488
    Location:281 → 369
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    71930639..71972323 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018229247.2 → XP_018084736.1  uncharacterized protein LOC734930 isoform X6

    UniProtKB/TrEMBL
    A0A8J0T9E0, A0A974H659
    Related
    ENSXLAP00005074855.1, ENSXLAT00005076435.1

  2. XM_041572161.1 → XP_041428095.1  uncharacterized protein LOC734930 isoform X2

    UniProtKB/TrEMBL
    A0A8J1LHD8, A0A974H659
    Related
    ENSXLAP00005075129.1, ENSXLAT00005076709.1
    Conserved Domains (3) summary
    PTZ00184
    Location:747 → 878
    PTZ00184; calmodulin; Provisional
    COG5069
    Location:36 → 299
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:402 → 625
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  3. XM_018229246.2 → XP_018084735.1  uncharacterized protein LOC734930 isoform X5

    UniProtKB/TrEMBL
    A0A1L8F929, A0A974C7I4, A0A974H659
    Related
    ENSXLAP00005075489.1, ENSXLAT00005077068.1

  4. XM_041572162.1 → XP_041428096.1  uncharacterized protein LOC734930 isoform X3

    UniProtKB/TrEMBL
    A0A8J1LFB3, A0A974H659
    Conserved Domains (3) summary
    PTZ00184
    Location:747 → 877
    PTZ00184; calmodulin; Provisional
    COG5069
    Location:36 → 299
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:402 → 625
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  5. XM_041572160.1 → XP_041428094.1  uncharacterized protein LOC734930 isoform X1

    UniProtKB/TrEMBL
    A0A8J1LGD2, A0A974H659
    Conserved Domains (3) summary
    PTZ00184
    Location:747 → 878
    PTZ00184; calmodulin; Provisional
    COG5069
    Location:36 → 299
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:402 → 625
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  6. XM_041572163.1 → XP_041428097.1  uncharacterized protein LOC734930 isoform X4

    UniProtKB/TrEMBL
    A0A8J1LEY6, A0A974H659
    Conserved Domains (3) summary
    PTZ00184
    Location:744 → 875
    PTZ00184; calmodulin; Provisional
    COG5069
    Location:36 → 296
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:399 → 622
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
Nucleotide Protein Strain
Heading Accession and Version

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