gna14.S guanine nucleotide binding protein (G protein), alpha 14 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: gna14.S
Official Full Name: guanine nucleotide binding protein (G protein), alpha 14 S homeolog
Primary source: Xenbase:XB-GENE-945101
Locus tag: XELAEV_18010132mg
See related: EnsemblRapid:ENSXLAG00005004461 AllianceGenome:Xenbase:XB-GENE-945101
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: gna14; gna14b; gna14-a; gna14-b
Summary: Predicted to enable several functions, including G-protein beta/gamma-subunit complex binding activity; GTP binding activity; and GTPase activity. Predicted to act upstream of or within action potential; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; and phospholipase C-activating dopamine receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Is expressed in cardiovascular system and urinary system. Orthologous to human GNA14 (G protein subunit alpha 14). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 1S

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (122265687..122331317, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (107504603..107570265, complement)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables G protein-coupled receptor binding	IEA Inferred from Electronic Annotation more info
enables G-protein beta/gamma-subunit complex binding	IEA Inferred from Electronic Annotation more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables guanyl nucleotide binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within action potential	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phospholipase C-activating dopamine receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of heterotrimeric G-protein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: guanine nucleotide binding protein (G protein), alpha 14 S homeolog

Names: guanine nucleotide binding protein (G protein), alpha 14 b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001096387.1 → NP_001089856.1 guanine nucleotide binding protein (G protein), alpha 14 S homeolog

See identical proteins and their annotated locations for NP_001089856.1

Status: PROVISIONAL

Source sequence(s)

BC108552

UniProtKB/TrEMBL

A0A974DUV0, Q32NN4

Related

ENSXLAP00005013339.1, ENSXLAT00005013521.1

Conserved Domains (2) summary

cd00066
Location:35 → 348

G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

smart00275
Location:15 → 352

G_alpha; G protein alpha subunit

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

122265687..122331317 complement

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GenBank, FASTA, Sequence Viewer (Graphics)