adi1.L acireductone dioxygenase 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: adi1.L
Official Full Name: acireductone dioxygenase 1 L homeolog
Primary source: Xenbase:XB-GENE-6255001
Locus tag: XELAEV_18028010mg
See related: EnsemblRapid:ENSXLAG00005030095 AllianceGenome:Xenbase:XB-GENE-6255001
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ARD'; adi1; Fe-ARD; Ni-ARD; mtcbp1; mtcbp-1
Summary: Predicted to enable oxidoreductase activity. Predicted to act upstream of or within L-methionine salvage from methylthioadenosine. Predicted to be located in cytoplasm; nucleus; and plasma membrane. Orthologous to human ADI1 (acireductone dioxygenase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 5L

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	5L	NC_054379.1 (145891944..145903057, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	5L	NC_030732.1 (134814902..134825870, complement)

Chromosome 5L - NC_054379.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables acireductone dioxygenase (Ni2+-requiring) activity	IEA Inferred from Electronic Annotation more info
enables acireductone dioxygenase [iron(II)-requiring] activity	IEA Inferred from Electronic Annotation more info
enables dioxygenase activity	IEA Inferred from Electronic Annotation more info
enables iron ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nickel cation binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within L-methionine salvage from methylthioadenosine	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within L-methionine salvage from methylthioadenosine	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within methionine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within methionine metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: acireductone dioxygenase; 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

Names: MTCBP-1; aci-reductone dioxygenase; acireductone dioxygenase (Ni(2+)-requiring); fe-ARD

NP_001089795.1

EC 1.13.11.53

EC 1.13.11.54

XP_041418261.1

EC 1.13.11.53

EC 1.13.11.54

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001096326.1 → NP_001089795.1 acireductone dioxygenase

See identical proteins and their annotated locations for NP_001089795.1

Status: PROVISIONAL

Source sequence(s)

BC106582

UniProtKB/Swiss-Prot

Q3B8C8

UniProtKB/TrEMBL

A0A974HK42

Conserved Domains (1) summary

pfam03079
Location:3 → 157

ARD; ARD/ARD' family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

145891944..145903057 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041562327.1 → XP_041418261.1 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase isoform X1

UniProtKB/TrEMBL

A0A8J1KLR7

Related

ENSXLAP00005089962.1, ENSXLAT00005091638.1

Conserved Domains (1) summary

cd02232
Location:28 → 140

cupin_ARD; acireductone dioxygenase (ARD), cupin domain