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pea15.L proliferation and apoptosis adaptor protein 15 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734852, updated on 4-Nov-2024

Summary

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Official Symbol
pea15.L
Official Full Name
proliferation and apoptosis adaptor protein 15 L homeolog
Primary source
Xenbase:XB-GENE-945189
Locus tag
XELAEV_18040661mg
See related
EnsemblRapid:ENSXLAG00005034302 AllianceGenome:Xenbase:XB-GENE-945189
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
pea15; pea-15; hummat1h; ped-pea15
Summary
Predicted to act upstream of or within MAPK cascade; apoptotic process; and regulation of apoptotic process. Predicted to be located in cytoplasm. Orthologous to human PEA15 (proliferation and apoptosis adaptor protein 15). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pea15.L in Genome Data Viewer
Location:
chromosome: 8L
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (128477914..128528702)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (113239092..113289720)

Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene ATPase, Na+/K+ transporting, alpha 2 polypeptide L homeolog Neighboring gene calsequestrin 1 L homeolog Neighboring gene uncharacterized LOC121397230 Neighboring gene uncharacterized LOC108699595

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC131326

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within MAPK cascade IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
proliferation and apoptosis adaptor protein 15 L homeolog
Names
phosphoprotein enriched in astrocytes 15 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096318.1 → NP_001089787.2  proliferation and apoptosis adaptor protein 15 L homeolog

    Status: PROVISIONAL

    Source sequence(s)
    BC106562
    UniProtKB/TrEMBL
    A0A1L8FCQ0, A0A974H9I6
    Related
    ENSXLAP00005102434.1, ENSXLAT00005104429.1
    Conserved Domains (1) summary
    cd08338
    Location:30 → 113
    DED_PEA15; Death Effector Domain of Astrocyte phosphoprotein PEA-15

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    128477914..128528702
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018229225.2 → XP_018084714.1  proliferation and apoptosis adaptor protein 15 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974CB34, Q3KPT6
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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