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ptp4a3.S protein tyrosine phosphatase type IVA, member 3 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734842, updated on 4-Nov-2024

Summary

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Official Symbol
ptp4a3.S
Official Full Name
protein tyrosine phosphatase type IVA, member 3 S homeolog
Primary source
Xenbase:XB-GENE-17336528
Locus tag
XELAEV_18034058mg
See related
EnsemblRapid:ENSXLAG00005021891 AllianceGenome:Xenbase:XB-GENE-17336528
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
prl3; prl-3; ptpcaax3
Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to act upstream of or within endothelial cell migration and protein dephosphorylation. Predicted to be located in cytoplasm and nucleus. Orthologous to human PTP4A3 (protein tyrosine phosphatase 4A3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ptp4a3.S in Genome Data Viewer
Location:
chromosome: 6S
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6S NC_054382.1 (132907847..132975822, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6S NC_030735.1 (124264694..124332611, complement)

Chromosome 6S - NC_054382.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108719766 Neighboring gene uncharacterized LOC108695462 Neighboring gene t-SNARE domain containing 1 S homeolog Neighboring gene adhesion G protein-coupled receptor B1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC131305

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within endothelial cell migration IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC734842

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096308.1 → NP_001089777.1  uncharacterized protein LOC734842

    See identical proteins and their annotated locations for NP_001089777.1

    Status: PREDICTED

    Source sequence(s)
    BC106545
    UniProtKB/TrEMBL
    Q3KPU9
    Related
    ENSXLAP00005064273.1, ENSXLAT00005065787.1
    Conserved Domains (1) summary
    cl21483
    Location:2 → 108
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054382.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    132907847..132975822 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018268812.2 → XP_018124301.1  uncharacterized protein LOC734842 isoform X1

    UniProtKB/TrEMBL
    A0A1L8FU16, A0A974CKH3
    Conserved Domains (1) summary
    cd18535
    Location:5 → 158
    PTP-IVa3; protein tyrosine phosphatase type IVA 3

  2. XM_041567254.1 → XP_041423188.1  uncharacterized protein LOC734842 isoform X1

    UniProtKB/TrEMBL
    A0A1L8FU16, A0A974CKH3
    Conserved Domains (1) summary
    cd18535
    Location:5 → 158
    PTP-IVa3; protein tyrosine phosphatase type IVA 3

  3. XM_018268813.2 → XP_018124302.1  uncharacterized protein LOC734842 isoform X1

    UniProtKB/TrEMBL
    A0A1L8FU16, A0A974CKH3
    Conserved Domains (1) summary
    cd18535
    Location:5 → 158
    PTP-IVa3; protein tyrosine phosphatase type IVA 3

  4. XM_018268810.2 → XP_018124299.1  uncharacterized protein LOC734842 isoform X1

    UniProtKB/TrEMBL
    A0A1L8FU16, A0A974CKH3
    Conserved Domains (1) summary
    cd18535
    Location:5 → 158
    PTP-IVa3; protein tyrosine phosphatase type IVA 3

  5. XM_041567250.1 → XP_041423184.1  uncharacterized protein LOC734842 isoform X1

    UniProtKB/TrEMBL
    A0A1L8FU16, A0A974CKH3
    Conserved Domains (1) summary
    cd18535
    Location:5 → 158
    PTP-IVa3; protein tyrosine phosphatase type IVA 3

  6. XM_018268811.2 → XP_018124300.1  uncharacterized protein LOC734842 isoform X1

    UniProtKB/TrEMBL
    A0A1L8FU16, A0A974CKH3
    Conserved Domains (1) summary
    cd18535
    Location:5 → 158
    PTP-IVa3; protein tyrosine phosphatase type IVA 3

  7. XM_041567252.1 → XP_041423186.1  uncharacterized protein LOC734842 isoform X1

    UniProtKB/TrEMBL
    A0A1L8FU16, A0A974CKH3
    Conserved Domains (1) summary
    cd18535
    Location:5 → 158
    PTP-IVa3; protein tyrosine phosphatase type IVA 3

  8. XM_041567248.1 → XP_041423182.1  uncharacterized protein LOC734842 isoform X1

    UniProtKB/TrEMBL
    A0A1L8FU16, A0A974CKH3
    Related
    ENSXLAP00005064288.1, ENSXLAT00005065802.1
    Conserved Domains (1) summary
    cd18535
    Location:5 → 158
    PTP-IVa3; protein tyrosine phosphatase type IVA 3

  9. XM_041567253.1 → XP_041423187.1  uncharacterized protein LOC734842 isoform X1

    UniProtKB/TrEMBL
    A0A1L8FU16, A0A974CKH3
    Conserved Domains (1) summary
    cd18535
    Location:5 → 158
    PTP-IVa3; protein tyrosine phosphatase type IVA 3

  10. XM_041567255.1 → XP_041423189.1  uncharacterized protein LOC734842 isoform X1

    UniProtKB/TrEMBL
    A0A1L8FU16, A0A974CKH3
    Conserved Domains (1) summary
    cd18535
    Location:5 → 158
    PTP-IVa3; protein tyrosine phosphatase type IVA 3

  11. XM_041567251.1 → XP_041423185.1  uncharacterized protein LOC734842 isoform X1

    UniProtKB/TrEMBL
    A0A1L8FU16, A0A974CKH3
    Conserved Domains (1) summary
    cd18535
    Location:5 → 158
    PTP-IVa3; protein tyrosine phosphatase type IVA 3
Nucleotide Protein Strain
Heading Accession and Version

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