lhpp.S phospholysine phosphohistidine inorganic pyrophosphate phosphatase S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: lhpp.S
Official Full Name: phospholysine phosphohistidine inorganic pyrophosphate phosphatase S homeolog
Primary source: Xenbase:XB-GENE-955679
Locus tag: XELAEV_18036849mg
See related: AllianceGenome:Xenbase:XB-GENE-955679
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: lhpp
Summary: Predicted to enable inorganic diphosphate phosphatase activity. Predicted to act upstream of or within phosphate-containing compound metabolic process. Predicted to be located in cytosol and nucleus. Orthologous to human LHPP (phospholysine phosphohistidine inorganic pyrophosphate phosphatase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 7S

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7S	NC_054384.1 (11516542..11536507, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7S	NC_030737.1 (11499800..11519837, complement)

Chromosome 7S - NC_054384.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables inorganic diphosphate phosphatase activity	IEA Inferred from Electronic Annotation more info
enables inorganic diphosphate phosphatase activity	ISS Inferred from Sequence or Structural Similarity more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within dephosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phosphate-containing compound metabolic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: phospholysine phosphohistidine inorganic pyrophosphate phosphatase

NP_001089769.1

EC 3.6.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001096300.1 → NP_001089769.1 phospholysine phosphohistidine inorganic pyrophosphate phosphatase

See identical proteins and their annotated locations for NP_001089769.1

Status: PROVISIONAL

Source sequence(s)

BC106524

UniProtKB/Swiss-Prot

Q3B8E3

UniProtKB/TrEMBL

A0A974CB50

Conserved Domains (3) summary

TIGR01458
Location:8 → 263

HAD-SF-IIA-hyp3; HAD-superfamily subfamily IIA hydrolase, TIGR01458

pfam13242
Location:184 → 258

Hydrolase_like; HAD-hyrolase-like

pfam13344
Location:11 → 111

Hydrolase_6; Haloacid dehalogenase-like hydrolase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

11516542..11536507 complement

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GenBank, FASTA, Sequence Viewer (Graphics)