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clk2.L CDC like kinase 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734822, updated on 18-Sep-2024

Summary

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Official Symbol
clk2.L
Official Full Name
CDC like kinase 2 L homeolog
Primary source
Xenbase:XB-GENE-922512
Locus tag
XELAEV_18040945mg
See related
EnsemblRapid:ENSXLAG00005003882
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
clk2
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Genomic context

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See clk2.L in Genome Data Viewer
Location:
chromosome: 8L
Exon count:
13
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (134812588..134824566, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (119552794..119565107, complement)

Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene secretory carrier membrane protein 3 L homeolog Neighboring gene complexin-3 Neighboring gene phosphatidylinositol 4-phosphate 5-kinase type-1 alpha-like Neighboring gene potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cdc2-like kinase 2 (Clk2) promotes early neural development in Xenopus embryos. Virgirinia RP, et al. Dev Growth Differ, 2019 Aug. PMID 31270814
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC131228

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of RNA splicing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CDC like kinase 2 L homeolog
Names
CDC-like kinase 2
NP_001089758.1
XP_018084709.1
XP_041428085.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096289.1 → NP_001089758.1  CDC like kinase 2 L homeolog

    See identical proteins and their annotated locations for NP_001089758.1

    Status: PROVISIONAL

    Source sequence(s)
    BC106497
    UniProtKB/TrEMBL
    A0A974H9A3, Q3KPX3
    Related
    ENSXLAP00005011676.1, ENSXLAT00005011850.1
    Conserved Domains (3) summary
    smart00220
    Location:165 → 481
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14215
    Location:152 → 481
    PKc_CLK2; Catalytic domain of the Dual-specificity protein kinase, CDC-like kinase 2
    pfam08648
    Location:53 → 110
    DUF1777; Protein of unknown function (DUF1777)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    134812588..134824566 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018229220.2 → XP_018084709.1  CDC like kinase 2 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J0THZ7, A0A974H9A3
    Related
    ENSXLAP00005011668.1, ENSXLAT00005011842.1

  2. XM_041572151.1 → XP_041428085.1  CDC like kinase 2 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1LHC6
    Conserved Domains (1) summary
    cl21453
    Location:1 → 251
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

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