XB5838589.L provisional ortholog of ADAM metallopeptidase domain 9 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Symbol: XB5838589.L
Full Name: provisional ortholog of ADAM metallopeptidase domain 9 L homeolog
Primary source: Xenbase:XB-GENE-5838602
Locus tag: XELAEV_18018512mg
See related: EnsemblRapid:ENSXLAG00005001039 AllianceGenome:Xenbase:XB-GENE-5838602
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: LOC100145070.L
Summary: Predicted to enable metal ion binding activity and metalloendopeptidase activity. Predicted to act upstream of or within male gonad development and proteolysis. Predicted to be located in external side of plasma membrane and sperm head plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 3L

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3L	NC_054375.1 (128221494..128245378)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3L	NC_030728.1 (112823272..112847687)

Chromosome 3L - NC_054375.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables metalloendopeptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within male gonad development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in sperm head plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uncharacterized protein LOC734770

Names: disintegrin and metalloproteinase domain-containing protein 9-like L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001096238.1 → NP_001089707.1 uncharacterized protein LOC734770

See identical proteins and their annotated locations for NP_001089707.1

Status: PREDICTED

Source sequence(s)

BC106375

UniProtKB/TrEMBL

A0A974HTV2, Q3KQ58

Related

ENSXLAP00005003132.1, ENSXLAT00005003194.1

Conserved Domains (3) summary

cd04269
Location:190 → 378

ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

pfam01421
Location:191 → 380

Reprolysin; Reprolysin (M12B) family zinc metalloprotease

pfam01562
Location:48 → 151

Pep_M12B_propep; Reprolysin family propeptide

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

128221494..128245378

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041585270.1 → XP_041441204.1 uncharacterized protein LOC734770 isoform X2

UniProtKB/TrEMBL

A0A8J1MHK6, A0A974HTV2

Conserved Domains (1) summary

cd04269
Location:190 → 357

ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
XM_018251252.2 → XP_018106741.1 uncharacterized protein LOC734770 isoform X1

UniProtKB/TrEMBL

A0A8J0US04, A0A974HTV2
XM_041585271.1 → XP_041441205.1 uncharacterized protein LOC734770 isoform X3

UniProtKB/TrEMBL

A0A8J1MJJ0, A0A974HTV2

Conserved Domains (1) summary

cd04269
Location:108 → 296

ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...