pds5b.L PDS5 cohesin associated factor B L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: pds5b.L
Official Full Name: PDS5 cohesin associated factor B L homeolog
Primary source: Xenbase:XB-GENE-6255297
Locus tag: XELAEV_18013718mg
See related: EnsemblRapid:ENSXLAG00005025217 AllianceGenome:Xenbase:XB-GENE-6255297
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: as3; aprin; pds5b; aprin-a; pds5b-a; pds5b-b
Summary: Predicted to enable DNA binding activity. Acts upstream of or within mitotic sister chromatid cohesion. Predicted to be located in nucleus. Orthologous to human PDS5B (PDS5 cohesin associated factor B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 2L

Exon count:: 36

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2L	NC_054373.1 (162105830..162180368, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2L	NC_030726.1 (156219911..156295095, complement)

Chromosome 2L - NC_054373.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mitotic sister chromatid cohesion	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within mitotic sister chromatid cohesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of cell population proliferation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in chromatin	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: sister chromatid cohesion protein PDS5 homolog B-A

Names: PDS5, regulator of cohesion maintenance, homolog B; androgen-induced proliferation inhibitor A; sister chromatid cohesion protein Pds5B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001096189.1 → NP_001089658.1 sister chromatid cohesion protein PDS5 homolog B-A

See identical proteins and their annotated locations for NP_001089658.1

Status: PROVISIONAL

Source sequence(s)

BC100220

UniProtKB/Swiss-Prot

Q498H0, Q4QXM2

UniProtKB/TrEMBL

A0A974DJG7

Related

ENSXLAP00005075285.1, ENSXLAT00005076865.1

Conserved Domains (3) summary

PLN02967
Location:1216 → 1344

PLN02967; kinase

PRK05667
Location:250 → 457

dnaG; DNA primase; Validated

sd00044
Location:240 → 261

HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

162105830..162180368 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041581112.1 → XP_041437046.1 sister chromatid cohesion protein PDS5 homolog B-A isoform X1

UniProtKB/TrEMBL

A0A1L8HIX8, A0A974DJG7, A0A974DRU0

Conserved Domains (3) summary

PLN02967
Location:1218 → 1346

PLN02967; kinase

sd00044
Location:242 → 263

HEAT; HEAT repeat [structural motif]

cd19953
Location:33 → 663

PDS5; Sister chromatid cohesion protein PDS5