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auh.S AU RNA binding protein/enoyl-CoA hydratase S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734576, updated on 4-Nov-2024

Summary

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Official Symbol
auh.S
Official Full Name
AU RNA binding protein/enoyl-CoA hydratase S homeolog
Primary source
Xenbase:XB-GENE-963004
Locus tag
XELAEV_18010200mg
See related
EnsemblRapid:ENSXLAG00005013050 AllianceGenome:Xenbase:XB-GENE-963004
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
auh
Summary
Predicted to enable enoyl-CoA hydratase activity. Predicted to act upstream of or within fatty acid beta-oxidation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 1 and renal tubular transport disease. Orthologous to human AUH (AU RNA binding methylglutaconyl-CoA hydratase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See auh.S in Genome Data Viewer
Location:
chromosome: 1S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (128716503..128855535, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (113877064..114017645, complement)

Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene DIRAS family GTP binding RAS like 2 S homeolog Neighboring gene spleen tyrosine kinase S homeolog Neighboring gene nuclear factor, interleukin 3 regulated S homeolog Neighboring gene receptor tyrosine kinase like orphan receptor 2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC115495

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables enoyl-CoA hydratase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within fatty acid beta-oxidation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
AU RNA binding protein/enoyl-CoA hydratase S homeolog
Names
AU RNA binding protein/enoyl-Coenzyme A hydratase
NP_001089522.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096053.1 → NP_001089522.1  AU RNA binding protein/enoyl-CoA hydratase S homeolog

    See identical proteins and their annotated locations for NP_001089522.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097787
    UniProtKB/TrEMBL
    A0A974DU64, Q4V7P4
    Related
    ENSXLAP00005038438.1, ENSXLAT00005039359.1
    Conserved Domains (1) summary
    cl23717
    Location:68 → 322
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    128716503..128855535 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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