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mmadhc.L metabolism of cobalamin associated D L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734540, updated on 4-Nov-2024

Summary

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Official Symbol
mmadhc.L
Official Full Name
metabolism of cobalamin associated D L homeolog
Primary source
Xenbase:XB-GENE-973167
Locus tag
XELAEV_18044565mg
See related
EnsemblRapid:ENSXLAG00005031149 AllianceGenome:Xenbase:XB-GENE-973167
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
mmadhc
Summary
Predicted to act upstream of or within cobalamin metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblD. Orthologous to human MMADHC (metabolism of cobalamin associated D). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See mmadhc.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (67892604..67912044, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (57374166..57393450, complement)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene LY6/PLAUR domain containing 6B L homeolog Neighboring gene uncharacterized LOC121398375 Neighboring gene LY6/PLAUR domain containing 6 L homeolog Neighboring gene uncharacterized LOC108701324 Neighboring gene Rho family GTPase 3 L homeolog Neighboring gene N-myc and STAT interactor L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC115384

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within cobalamin metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
metabolism of cobalamin associated D L homeolog
Names
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
methylmalonic aciduria and homocystinuria, cblD type L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096020.1 → NP_001089489.1  metabolism of cobalamin associated D L homeolog

    See identical proteins and their annotated locations for NP_001089489.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097712
    UniProtKB/TrEMBL
    A0A974H3H1, Q4V7U5
    Related
    ENSXLAP00005093307.1, ENSXLAT00005094990.1
    Conserved Domains (1) summary
    pfam10229
    Location:24 → 294
    DUF2246; Uncharacterized conserved protein (DUF2246)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    67892604..67912044 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018234588.2 → XP_018090077.1  metabolism of cobalamin associated D L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974H3H1, Q4V7U5

  2. XM_018234587.2 → XP_018090076.1  metabolism of cobalamin associated D L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974H3H1, Q4V7U5
    Related
    ENSXLAP00005093274.1, ENSXLAT00005094956.1

  3. XM_041575746.1 → XP_041431680.1  metabolism of cobalamin associated D L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1LSH6
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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