dpm1.S dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: dpm1.S
Official Full Name: dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit S homeolog
Primary source: Xenbase:XB-GENE-976628
Locus tag: XELAEV_18046183mg
See related: EnsemblRapid:ENSXLAG00005032386 AllianceGenome:Xenbase:XB-GENE-976628
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: dpm1
Summary: Predicted to enable dolichyl-phosphate beta-D-mannosyltransferase activity and dolichyl-phosphate-mannose-protein mannosyltransferase activity. Predicted to act upstream of or within GPI anchor biosynthetic process and protein O-linked mannosylation. Predicted to be located in endoplasmic reticulum membrane. Is expressed in ectoderm and nervous system. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ie. Orthologous to human DPM1 (dolichyl-phosphate mannosyltransferase subunit 1, catalytic). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 9_10S

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10S	NC_054388.1 (10098674..10112923, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10S	NC_030741.1 (9984544..9998793, complement)

Chromosome 9_10S - NC_054388.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables dolichyl-phosphate beta-D-mannosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables dolichyl-phosphate beta-D-mannosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables dolichyl-phosphate-mannose-protein mannosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within GPI anchor biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within GPI anchor biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within dolichol-linked oligosaccharide biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein O-linked mannosylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein O-linked mannosylation	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within protein glycosylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein mannosylation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit S homeolog

NP_001089465.1

EC 2.4.1.83

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001095996.1 → NP_001089465.1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit S homeolog

See identical proteins and their annotated locations for NP_001089465.1

Status: PROVISIONAL

Source sequence(s)

BC097635

UniProtKB/TrEMBL

A0A974BT92, Q4QR31

Related

ENSXLAP00005097170.1, ENSXLAT00005098956.1

Conserved Domains (2) summary

cd06442
Location:16 → 243

DPM1_like; DPM1_like represents putative enzymes similar to eukaryotic DPM1

PLN02726
Location:7 → 247

PLN02726; dolichyl-phosphate beta-D-mannosyltransferase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

10098674..10112923 complement

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GenBank, FASTA, Sequence Viewer (Graphics)