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dcxr.L dicarbonyl/L-xylulose reductase L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734498, updated on 4-Nov-2024

Summary

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Official Symbol
dcxr.L
Official Full Name
dicarbonyl/L-xylulose reductase L homeolog
Primary source
Xenbase:XB-GENE-990332
Locus tag
XELAEV_18043673mg
See related
EnsemblRapid:ENSXLAG00005024943 AllianceGenome:Xenbase:XB-GENE-990332
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
dcxr
Summary
Predicted to enable L-xylulose reductase (NADPH) activity and carbonyl reductase (NADPH) activity. Predicted to act upstream of or within glucose metabolic process and xylulose metabolic process. Human ortholog(s) of this gene implicated in pentosuria. Orthologous to human DCXR (dicarbonyl and L-xylulose reductase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See dcxr.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (24755583..24769115, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (19324003..19337646)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 45 L homeolog Neighboring gene ras-related C3 botulinum toxin substrate 3 Neighboring gene uncharacterized LOC108705691 Neighboring gene dual specificity phosphatase 3 L homeolog Neighboring gene C-C chemokine receptor type 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC114658

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables L-xylulose reductase (NADPH) activity IEA
Inferred from Electronic Annotation
more info
  
enables carbonyl reductase (NADPH) activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within glucose metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within small molecule metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within xylulose metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
L-xylulose reductase
NP_001089448.1
XP_018090068.1
XP_041431679.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095979.1 → NP_001089448.1  L-xylulose reductase

    See identical proteins and their annotated locations for NP_001089448.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097532
    UniProtKB/TrEMBL
    A0A974BX69, A0A974BX97, Q4QR61
    Related
    ENSXLAP00005074146.1, ENSXLAT00005075717.1
    Conserved Domains (2) summary
    PRK07060
    Location:1 → 243
    PRK07060; short chain dehydrogenase; Provisional
    cd05351
    Location:1 → 244
    XR_like_SDR_c; xylulose reductase-like, classical (c) SDRs

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    24755583..24769115 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018234579.2 → XP_018090068.1  L-xylulose reductase isoform X1

    UniProtKB/TrEMBL
    A0A8J0TSH4, A0A974BX69
    Related
    ENSXLAP00005074117.1, ENSXLAT00005075688.1

  2. XM_041575745.1 → XP_041431679.1  L-xylulose reductase isoform X2

    UniProtKB/TrEMBL
    A0A8J1LQZ4, A0A974BX69
    Related
    ENSXLAP00005074068.1, ENSXLAT00005075638.1
    Conserved Domains (1) summary
    cd05351
    Location:10 → 236
    XR_like_SDR_c; xylulose reductase-like, classical (c) SDRs
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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