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vps37a.L vacuolar protein sorting 37 homolog A L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734384, updated on 4-Nov-2024

Summary

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Official Symbol
vps37a.L
Official Full Name
vacuolar protein sorting 37 homolog A L homeolog
Primary source
Xenbase:XB-GENE-969339
Locus tag
XELAEV_18005320mg
See related
EnsemblRapid:ENSXLAG00005006292 AllianceGenome:Xenbase:XB-GENE-969339
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
vps37a
Summary
Predicted to act upstream of or within protein targeting to membrane; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be located in late endosome membrane. Predicted to be part of ESCRT I complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 53. Orthologous to human VPS37A (VPS37A subunit of ESCRT-I). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See vps37a.L in Genome Data Viewer
Location:
chromosome: 1L
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (44244665..44270702, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (34994347..35016442, complement)

Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene protein FAM135A-like Neighboring gene protein FAM135A-like Neighboring gene CCR4-NOT transcription complex subunit 7-like Neighboring gene protein FAM135A-like Neighboring gene protein FAM135A-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC115147

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein targeting to membrane IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein targeting to vacuole IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ESCRT I complex IEA
Inferred from Electronic Annotation
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in late endosome membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
vacuolar protein sorting 37 homolog A L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095865.1 → NP_001089334.1  vacuolar protein sorting 37 homolog A L homeolog

    See identical proteins and their annotated locations for NP_001089334.1

    Status: PROVISIONAL

    Source sequence(s)
    BC123211
    UniProtKB/TrEMBL
    A0A974DU55, Q0IHC8
    Related
    ENSXLAP00005018711.1, ENSXLAT00005019046.1
    Conserved Domains (1) summary
    pfam07200
    Location:219 → 359
    Mod_r; Modifier of rudimentary (Mod(r)) protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    44244665..44270702 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041582774.1 → XP_041438708.1  vacuolar protein sorting 37 homolog A L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8HU43, A0A974DU55, A0A974DX44
    Conserved Domains (1) summary
    pfam07200
    Location:219 → 363
    Mod_r; Modifier of rudimentary (Mod(r)) protein

  2. XM_018249782.2 → XP_018105271.1  vacuolar protein sorting 37 homolog A L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8HU43, A0A974DU55, A0A974DX44
    Conserved Domains (1) summary
    pfam07200
    Location:219 → 363
    Mod_r; Modifier of rudimentary (Mod(r)) protein
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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