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tmx2.S thioredoxin related transmembrane protein 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734381, updated on 4-Nov-2024

Summary

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Official Symbol
tmx2.S
Official Full Name
thioredoxin related transmembrane protein 2 S homeolog
Primary source
Xenbase:XB-GENE-865871
Locus tag
XELAEV_180372601mg
See related
EnsemblRapid:ENSXLAG00005018880 AllianceGenome:Xenbase:XB-GENE-865871
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tmx2; tmx2.L; txndc14
Summary
Predicted to enable disulfide oxidoreductase activity. Predicted to act upstream of or within brain development. Predicted to be located in endoplasmic reticulum membrane and mitochondrial membrane. Predicted to be active in mitochondria-associated endoplasmic reticulum membrane contact site. Orthologous to human TMX2 (thioredoxin related transmembrane protein 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tmx2.S in Genome Data Viewer
Location:
chromosome: 7S
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7S NC_054384.1 (48132975..48176783, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7S NC_030737.1 (39581668..39615509)

Chromosome 7S - NC_054384.1Genomic Context describing neighboring genes Neighboring gene calsyntenin-1 Neighboring gene uncharacterized histidine-rich protein DDB_G0274557-like Neighboring gene uncharacterized LOC108704126 Neighboring gene uncharacterized LOC121396348 Neighboring gene myb-related transcription factor, partner of profilin-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC114725

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables disulfide oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables disulfide oxidoreductase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within brain development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within brain development ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondria-associated endoplasmic reticulum membrane contact site ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
thioredoxin-related transmembrane protein 2
Names
thioredoxin domain-containing protein 14
thioredoxin-related transmembrane protein 2 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095862.1 → NP_001089331.1  thioredoxin-related transmembrane protein 2 precursor

    See identical proteins and their annotated locations for NP_001089331.1

    Status: PROVISIONAL

    Source sequence(s)
    BC092100
    UniProtKB/Swiss-Prot
    Q58E26
    Related
    ENSXLAP00005055720.1, ENSXLAT00005056939.1
    Conserved Domains (1) summary
    cd02962
    Location:109 → 259
    TMX2; TMX2 family; composed of proteins similar to human TMX2, a 372-amino acid TRX-related transmembrane protein, identified and characterized through the cloning of its cDNA from a human fetal library. It contains a TRX domain but the redox active CXXC motif ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    48132975..48176783 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q58E26.1 GenPept UniProtKB/Swiss-Prot:Q58E26

Gene LinkOut

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