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spdl1.L spindle apparatus coiled-coil protein 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734358, updated on 4-Nov-2024

Summary

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Official Symbol
spdl1.L
Official Full Name
spindle apparatus coiled-coil protein 1 L homeolog
Primary source
Xenbase:XB-GENE-5754977
Locus tag
XELAEV_18017129mg
See related
EnsemblRapid:ENSXLAG00005000251 AllianceGenome:Xenbase:XB-GENE-5754977
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
spdl1; ccdc99; spdl1-a; spdl1.S; spindly; ccdc99-a; ccdc99-b
Summary
Predicted to enable kinetochore binding activity. Predicted to act upstream of or within establishment of mitotic spindle orientation; mitotic metaphase chromosome alignment; and protein localization to kinetochore. Predicted to be located in nucleus and spindle pole. Predicted to be part of outer kinetochore. Is expressed in ectoderm; nervous system; pharyngeal arch; and urinary system. Orthologous to human SPDL1 (spindle apparatus coiled-coil protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See spdl1.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (39421270..39449748, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (25920045..25948693, complement)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene forkhead box I1 L homeolog Neighboring gene dedicator of cytokinesis 2 L homeolog Neighboring gene protein INSYN2B Neighboring gene slit guidance ligand 3 L homeolog Neighboring gene protein spinster homolog 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC85118

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables kinetochore binding IEA
Inferred from Electronic Annotation
more info
  
enables kinetochore binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within establishment of mitotic spindle orientation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within establishment of mitotic spindle orientation ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within mitotic metaphase chromosome alignment IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mitotic metaphase chromosome alignment ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within mitotic spindle assembly checkpoint signaling IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein localization to kinetochore IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein localization to kinetochore ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of outer kinetochore IEA
Inferred from Electronic Annotation
more info
  
part_of outer kinetochore ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
  
located_in spindle pole ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
protein Spindly-A
Names
coiled-coil domain containing 99
spindle apparatus coiled-coil protein 1 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095839.1 → NP_001089308.1  protein Spindly-A

    See identical proteins and their annotated locations for NP_001089308.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091716
    UniProtKB/Swiss-Prot
    Q5BIX7
    UniProtKB/TrEMBL
    A0A974HS48
    Related
    ENSXLAP00005000662.1, ENSXLAT00005000689.1
    Conserved Domains (1) summary
    cl03951
    Location:39 → 136
    CDC37_N; Cdc37 N terminal kinase binding

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    39421270..39449748 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5BIX7.1 GenPept UniProtKB/Swiss-Prot:Q5BIX7

Gene LinkOut

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