U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

prpf18.L pre-mRNA processing factor 18 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734335, updated on 4-Nov-2024

Summary

Official Symbol
prpf18.L
Official Full Name
pre-mRNA processing factor 18 L homeolog
Primary source
Xenbase:XB-GENE-5838471
Locus tag
XELAEV_18045316mg
See related
EnsemblRapid:ENSXLAG00005013443 AllianceGenome:Xenbase:XB-GENE-5838471
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
prpf18
Summary
Predicted to act upstream of or within generation of catalytic spliceosome for second transesterification step. Predicted to be located in nuclear speck. Predicted to be part of U2-type post-spliceosomal complex; U4/U6 x U5 tri-snRNP complex; and U5 snRNP. Orthologous to human PRPF18 (pre-mRNA processing factor 18). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See prpf18.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (110827466..110839652)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (100258340..100270518)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 1 L homeolog Neighboring gene aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog Neighboring gene aldolase, fructose-bisphosphate B L homeolog Neighboring gene uncharacterized LOC108701588

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • MGC85069

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within generation of catalytic spliceosome for second transesterification step IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of U2-type post-spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 
part_of U4/U6 x U5 tri-snRNP complex IEA
Inferred from Electronic Annotation
more info
 
part_of U5 snRNP IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
pre-mRNA-splicing factor 18
Names
PRP18 homolog
PRP18 pre-mRNA processing factor 18 homolog

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095818.1NP_001089287.1  pre-mRNA-splicing factor 18

    See identical proteins and their annotated locations for NP_001089287.1

    Status: PROVISIONAL

    Source sequence(s)
    BC090228
    UniProtKB/Swiss-Prot
    Q5EAV6
    UniProtKB/TrEMBL
    A0A974C078, A0A974C171
    Related
    ENSXLAP00005039711.1, ENSXLAT00005040631.1
    Conserved Domains (2) summary
    smart00500
    Location:79122
    SFM; Splicing Factor Motif, present in Prp18 and Pr04
    pfam02840
    Location:192328
    Prp18; Prp18 domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    110827466..110839652
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)