cdc42se2l.S CDC42 small effector 2 like S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: cdc42se2l.S
Official Full Name: CDC42 small effector 2 like S homeolog
Primary source: Xenbase:XB-GENE-6493981
Locus tag: XELAEV_18010205mg
See related: EnsemblRapid:ENSXLAG00005012275
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: spec2; cdc42se2; cdc42se2-a; cdc42se2-b
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Genomic context

Location:: chromosome: 1S

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (129335711..129400903, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (114376441..114441425, complement)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables small GTPase binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of Rho protein signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of cell shape	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of signal transduction	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: CDC42 small effector protein 2-A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001171726.1 → NP_001165197.1 CDC42 small effector protein 2-A

See identical proteins and their annotated locations for NP_001165197.1

Status: PROVISIONAL

Source sequence(s)

BC090055

UniProtKB/Swiss-Prot

Q5FVD7

UniProtKB/TrEMBL

A0A1L8HPI8, A0A974DW62

Conserved Domains (1) summary

cd00132
Location:27 → 67

CRIB; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

129335711..129400903 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041576425.1 → XP_041432359.1 CDC42 small effector protein 2-A isoform X1

UniProtKB/Swiss-Prot

Q5FVD7

UniProtKB/TrEMBL

A0A1L8HPI8, A0A974DW62

Related

ENSXLAP00005035999.1, ENSXLAT00005036899.1

Conserved Domains (1) summary

cd00132
Location:27 → 67

CRIB; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...