alox12b.S arachidonate 12-lipoxygenase, 12R type S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: alox12b.S
Official Full Name: arachidonate 12-lipoxygenase, 12R type S homeolog
Primary source: Xenbase:XB-GENE-5909112
Locus tag: XELAEV_18016554mg
See related: EnsemblRapid:ENSXLAG00005014273
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: 12r-lox; alox12b
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 2S

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2S	NC_054374.1 (168583940..168603078)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2S	NC_030727.1 (159071576..159088205)

Chromosome 2S - NC_054374.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables dioxygenase activity	IEA Inferred from Electronic Annotation more info
enables iron ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lipid oxidation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: arachidonate 12-lipoxygenase, 12R type S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001095796.1 → NP_001089265.1 arachidonate 12-lipoxygenase, 12R type S homeolog

See identical proteins and their annotated locations for NP_001089265.1

Status: PROVISIONAL

Source sequence(s)

BC089299

UniProtKB/TrEMBL

A0A974HX75, Q5FWK8

Related

ENSXLAP00005041936.1, ENSXLAT00005042982.1

Conserved Domains (2) summary

cd01753
Location:2 → 116

PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...

pfam00305
Location:227 → 654

Lipoxygenase; Lipoxygenase