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rnf41.S ring finger protein 41 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734308, updated on 4-Nov-2024

Summary

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Official Symbol
rnf41.S
Official Full Name
ring finger protein 41 S homeolog
Primary source
Xenbase:XB-GENE-943151
Locus tag
XELAEV_18015859mg
See related
EnsemblRapid:ENSXLAG00005033170 AllianceGenome:Xenbase:XB-GENE-943151
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
flrf; nrdp1; rnf41
Summary
Predicted to enable ubiquitin-protein transferase activity. Predicted to act upstream of or within extrinsic apoptotic signaling pathway and protein polyubiquitination. Predicted to be located in endoplasmic reticulum tubular network. Human ortholog(s) of this gene implicated in congenital heart disease. Orthologous to human RNF41 (ring finger protein 41). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See rnf41.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (129040085..129064695)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (120032394..120057005)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 52 S homeolog Neighboring gene nucleic acid binding protein 2 S homeolog Neighboring gene transfer RNA serine (anticodon CGA) Neighboring gene SWI/SNF related BAF chromatin remodeling complex subunit C2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC85030

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-protein transferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within extrinsic apoptotic signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within protein polyubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum tubular network IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
E3 ubiquitin-protein ligase NRDP1
Names
RING-type E3 ubiquitin transferase NRDP1
ring finger protein 41, E3 ubiquitin protein ligase S homeolog
NP_001089261.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095792.1 → NP_001089261.1  E3 ubiquitin-protein ligase NRDP1

    See identical proteins and their annotated locations for NP_001089261.1

    Status: PROVISIONAL

    Source sequence(s)
    BC089294
    UniProtKB/Swiss-Prot
    Q5FWL3
    UniProtKB/TrEMBL
    A0A974HWJ6
    Related
    ENSXLAP00005099204.1, ENSXLAT00005101076.1
    Conserved Domains (2) summary
    cd00162
    Location:18 → 55
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam08941
    Location:137 → 315
    USP8_interact; USP8 interacting

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    129040085..129064695
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5FWL3.1 GenPept UniProtKB/Swiss-Prot:Q5FWL3

Gene LinkOut

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