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cep57l1.L centrosomal protein 57kDa-like 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734283, updated on 4-Nov-2024

Summary

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Official Symbol
cep57l1.L
Official Full Name
centrosomal protein 57kDa-like 1 L homeolog
Primary source
Xenbase:XB-GENE-5897421
Locus tag
XELAEV_18027199mg
See related
EnsemblRapid:ENSXLAG00005034448 AllianceGenome:Xenbase:XB-GENE-5897421
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cep57; XCep57; cep57r; cep57l1; c6orf182
Summary
Enables gamma-tubulin binding activity. Acts upstream of or within attachment of spindle microtubules to kinetochore. Located in centrosome; kinetochore; and spindle microtubule. Orthologous to human CEP57L1 (centrosomal protein 57 like 1). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See cep57l1.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (81425245..81436724, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (79219983..79231379, complement)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene sialomucin core protein 24 Neighboring gene coiled-coil domain containing 162 L homeolog Neighboring gene sestrin 1 L homeolog Neighboring gene armadillo repeat containing 2 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Xenopus Cep57 is a novel kinetochore component involved in microtubule attachment. Emanuele MJ, et al. Cell, 2007 Sep 7. PMID 17803911
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC84957

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables gamma-tubulin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables gamma-tubulin binding IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
  
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within attachment of spindle microtubules to kinetochore IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in centrosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore IDA
Inferred from Direct Assay
more info
 PubMed 
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in spindle IEA
Inferred from Electronic Annotation
more info
  
located_in spindle microtubule IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
centrosomal protein cep57l1
Names
Centrosomal protein of 57 kDa
Cep57-related protein
centrosomal protein 57kDa
centrosomal protein 57kDa-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095767.1 → NP_001089236.1  centrosomal protein cep57l1

    See identical proteins and their annotated locations for NP_001089236.1

    Status: PROVISIONAL

    Source sequence(s)
    BC089255
    UniProtKB/Swiss-Prot
    Q5FWP9
    UniProtKB/TrEMBL
    A0A974HJJ8
    Related
    ENSXLAP00005102983.1, ENSXLAT00005104987.1
    Conserved Domains (3) summary
    pfam01496
    Location:126 → 204
    V_ATPase_I; V-type ATPase 116kDa subunit family
    pfam06657
    Location:341 → 408
    Cep57_MT_bd; Centrosome microtubule-binding domain of Cep57
    pfam14073
    Location:56 → 230
    Cep57_CLD; Centrosome localization domain of Cep57

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    81425245..81436724 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5FWP9.1 GenPept UniProtKB/Swiss-Prot:Q5FWP9

Gene LinkOut

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