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apob.S apolipoprotein B S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 734271, updated on 4-Nov-2024

Summary

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Official Symbol
apob.S
Official Full Name
apolipoprotein B S homeolog
Primary source
Xenbase:XB-GENE-17342638
Locus tag
XELAEV_18030121mg
See related
AllianceGenome:Xenbase:XB-GENE-17342638
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
fldb; ldlcq4
Summary
Predicted to enable cholesterol transfer activity and low-density lipoprotein particle receptor binding activity. Predicted to act upstream of or within several processes, including cholesterol homeostasis; lipoprotein transport; and triglyceride mobilization. Predicted to be located in cytoplasm; extracellular region; and lipid droplet. Predicted to be part of low-density lipoprotein particle; mature chylomicron; and very-low-density lipoprotein particle. Is expressed in musculoskeletal system. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Orthologous to human APOB (apolipoprotein B). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See apob.S in Genome Data Viewer
Location:
chromosome: 5S
Exon count:
2
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5S NC_054380.1 (131366675..131370024, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5S NC_030733.1 (124646583..124649932, complement)

Chromosome 5S - NC_054380.1Genomic Context describing neighboring genes Neighboring gene lipid droplet-associated hydrolase-like Neighboring gene growth differentiation factor 7 S homeolog Neighboring gene tudor domain containing 15 S homeolog Neighboring gene uncharacterized LOC121394323

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC98794

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables cholesterol transfer activity IEA
Inferred from Electronic Annotation
more info
  
enables low-density lipoprotein particle receptor binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cholesterol transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipoprotein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within triglyceride mobilization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of chylomicron IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
  
part_of low-density lipoprotein particle IEA
Inferred from Electronic Annotation
more info
  
part_of mature chylomicron IEA
Inferred from Electronic Annotation
more info
  
part_of very-low-density lipoprotein particle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC734271

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095755.1 → NP_001089224.1  uncharacterized protein LOC734271

    See identical proteins and their annotated locations for NP_001089224.1

    Status: PREDICTED

    Source sequence(s)
    BC089165
    UniProtKB/TrEMBL
    Q5FWX5

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054380.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    131366675..131370024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
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