ca5b carbonic anhydrase VB, mitochondrial [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: ca5bprovided by Xenbase
Official Full Name: carbonic anhydrase VB, mitochondrialprovided by Xenbase
Primary source: Xenbase:XB-GENE-1003819
See related: Ensembl:ENSXETG00000016594 AllianceGenome:Xenbase:XB-GENE-1003819
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable carbonate dehydratase activity and zinc ion binding activity. Predicted to act upstream of or within monoatomic ion homeostasis. Orthologous to human CA5B (carbonic anhydrase 5B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	4	NC_030680.2 (65764828..65798954, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	4	NC_030680.1 (68195966..68227936, complement)

Chromosome 4 - NC_030680.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables carbonate dehydratase activity	IEA Inferred from Electronic Annotation more info
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within monoatomic ion homeostasis	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: carbonic anhydrase 5A, mitochondrial

NP_001039155.1

EC 4.2.1.1

XP_012816720.2

EC 4.2.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001045690.1 → NP_001039155.1 carbonic anhydrase 5A, mitochondrial

See identical proteins and their annotated locations for NP_001039155.1

Status: PROVISIONAL

Source sequence(s)

CR942587

UniProtKB/TrEMBL

F6WLX6, Q28BX3

Related

ENSXETP00000036200.4, ENSXETT00000036200.5

Conserved Domains (1) summary

cd03118
Location:63 → 298

alpha_CA_V; Carbonic anhydrase alpha, CA isozyme V_like subgroup. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

65764828..65798954 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_012961266.3 → XP_012816720.2 carbonic anhydrase 5A, mitochondrial isoform X1

UniProtKB/TrEMBL

A0A6I8RDI3

Related

ENSXETP00000083590.2, ENSXETT00000075878.2

Conserved Domains (1) summary

cd03118
Location:53 → 288

alpha_CA_V; Carbonic anhydrase alpha, CA isozyme V_like subgroup. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...