lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: lssprovided by Xenbase
Official Full Name: lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)provided by Xenbase
Primary source: Xenbase:XB-GENE-5786978
See related: Ensembl:ENSXETG00000004899
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: xlss
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	9	NC_030685.2 (61031577..61054245, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	9	NC_030685.1 (55919357..55942404, complement)

Chromosome 9 - NC_030685.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables intramolecular transferase activity	IEA Inferred from Electronic Annotation more info
enables isomerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within triterpenoid biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in lipid droplet	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: lanosterol synthase

NP_001073038.1

EC 5.4.99.7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001079570.1 → NP_001073038.1 lanosterol synthase

See identical proteins and their annotated locations for NP_001073038.1

Status: PROVISIONAL

Source sequence(s)

BC122933

UniProtKB/TrEMBL

A0A6I8Q9P4, Q0IHW7

Related

ENSXETP00000069424.2, ENSXETT00000072914.2

Conserved Domains (1) summary

cd02892
Location:77 → 715

SQCY_1; Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization ...