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MAPRE1 microtubule associated protein RP/EB family member 1 [ Sus scrofa (pig) ]

Gene ID: 733687, updated on 17-Aug-2024

Summary

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Official Symbol
MAPRE1provided by VGNC
Official Full Name
microtubule associated protein RP/EB family member 1provided by VGNC
Primary source
VGNC:VGNC:96410
See related
Ensembl:ENSSSCG00000007253
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
Mapre3
Expression
Ubiquitous expression in spleen (RPKM 26.1), lung (RPKM 22.4) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See MAPRE1 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
8
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 17 NC_010459.5 (36390698..36426435)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 17 NC_010459.4 (41327542..41359142)

Chromosome 17 - NC_010459.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102161730 Neighboring gene DNA methyltransferase 3 beta Neighboring gene EF-hand calcium binding domain 8 Neighboring gene Sad1 and UNC84 domain containing 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends. Reid TA, et al. Elife, 2019 Sep 3. PMID 31478831, Free PMC Article
  2. The size of the EB cap determines instantaneous microtubule stability. Duellberg C, et al. Elife, 2016 Apr 6. PMID 27050486, Free PMC Article
  3. Interactions between EB1 and microtubules: dramatic effect of affinity tags and evidence for cooperative behavior. Zhu ZC, et al. J Biol Chem, 2009 Nov 20. PMID 19778897, Free PMC Article
  4. Full-length cDNA, molecular characterization and physical mapping of five genes from a porcine fetal cDNA library. Wang HL, et al. Anim Genet, 2006 Feb. PMID 16441306
  5. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Together, these results suggest that microtubule structural recognition, based on a fundamental diffusion-limited binding model, facilitates the tip tracking of EB1 at growing microtubule ends.
    Title: Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends.
  2. The authors show that the protective caps at microtubule ends are formed by the extended binding regions of EB proteins.
    Title: The size of the EB cap determines instantaneous microtubule stability.
  3. EB1-tubulin interactions are mediated in part by the same tubulin acidic tails utilized by other MAPs
    Title: Interactions between EB1 and microtubules: dramatic effect of affinity tags and evidence for cooperative behavior.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables microtubule plus-end binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein localization to microtubule plus-end IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of microtubule polymerization or depolymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in spindle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic microtubule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microtubule organizing center IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microtubule plus-end IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in spindle midzone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
microtubule-associated protein RP/EB family member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044613.1 → NP_001038078.1  microtubule-associated protein RP/EB family member 1

    See identical proteins and their annotated locations for NP_001038078.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ225363
    UniProtKB/TrEMBL
    A0A4X1SZV0, A0A4X1T1C1, A0A8W4FP63, Q2XVP5
    Related
    ENSSSCP00000007723.2, ENSSSCT00000007936.4
    Conserved Domains (1) summary
    cl26556
    Location:16 → 257
    EB1; EB1-like C-terminal motif

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010459.5 Reference Sscrofa11.1 Primary Assembly

    Range
    36390698..36426435
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005672836.3 → XP_005672893.1  microtubule-associated protein RP/EB family member 1 isoform X1

    See identical proteins and their annotated locations for XP_005672893.1

    UniProtKB/TrEMBL
    A0A4X1SZV0, A0A4X1T1C1, A0A8W4FP63, Q2XVP5
    Conserved Domains (1) summary
    cl26556
    Location:16 → 257
    EB1; EB1-like C-terminal motif

  2. XM_021077333.1 → XP_020932992.1  microtubule-associated protein RP/EB family member 1 isoform X1

    UniProtKB/TrEMBL
    A0A4X1SZV0, A0A4X1T1C1, A0A8W4FP63, Q2XVP5
    Conserved Domains (1) summary
    cl26556
    Location:16 → 257
    EB1; EB1-like C-terminal motif

  3. XM_021077334.1 → XP_020932993.1  microtubule-associated protein RP/EB family member 1 isoform X1

    UniProtKB/TrEMBL
    A0A4X1SZV0, A0A4X1T1C1, A0A8W4FP63, Q2XVP5
    Conserved Domains (1) summary
    cl26556
    Location:16 → 257
    EB1; EB1-like C-terminal motif
Nucleotide Protein
Heading Accession and Version

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