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ANG angiogenin [ Sus scrofa (pig) ]

Gene ID: 733639, updated on 5-Mar-2024

Summary

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Gene symbol
ANG
Gene description
angiogenin
See related
Ensembl:ENSSSCG00000059608
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
ANG1
Expression
Biased expression in liver (RPKM 275.5), mixtures (RPKM 113.2) and 3 other tissues See more
Orthologs
human mouse all
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Genomic context

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See ANG in Genome Data Viewer
Location:
chromosome: 7
Exon count:
3
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 7 NC_010449.5 (78249479..78262846, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) Unplaced Scaffold NW_003537709.2 (141295..154314)

Chromosome 7 - NC_010449.5Genomic Context describing neighboring genes Neighboring gene epididymal protein 3B Neighboring gene ribonuclease A family member 4 Neighboring gene transfer RNA proline (anticodon UGG) Neighboring gene transfer RNA tyrosine (anticodon GUA)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Relationship between RNASE1, ANG and RNASE6 gene polymorphism and the values of blood indices in suckling piglets. Szymańska H, et al. Acta Vet Hung, 2019 Sep. PMID 31549540
  2. The porcine ANG, RNASE1 and RNASE6 genes: molecular cloning, polymorphism detection and the association with haematological parameters. Bai X, et al. Mol Biol Rep, 2009 Nov. PMID 19247805
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Anaemia was more common in younger piglets with RNASE1 GA genotype. ANG gene polymorphism was associated with the severity of iron deficiency in younger piglets. Varying levels of iron status and red blood cell indices in RNASE6 genotypes presumably resulted from the coupling of genes involved in iron metabolism and expressed in an age-dependent manner.
    Title: Relationship between RNASE1, ANG and RNASE6 gene polymorphism and the values of blood indices in suckling piglets.
  2. Association analyses revealed the significant associations (P < 0.05) between the porcine ANG g. 149G>T polymorphism and mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean platelet volume (MPV) and platelet-large cell ratio (P-LCR).
    Title: The porcine ANG, RNASE1 and RNASE6 genes: molecular cloning, polymorphism detection and the association with haematological parameters.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA nuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in antibacterial humoral response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to Gram-positive bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
angiogenin
Names
RNase 5
Ribonuclease 5
NP_001038038.1
XP_020954026.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044573.2 → NP_001038038.1  angiogenin precursor

    See identical proteins and their annotated locations for NP_001038038.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ498979
    UniProtKB/TrEMBL
    A0A287A0F3, A0A8D0LNL7, A0A8D0QG20, A0A8D1GP79, Q1HDU1
    Related
    ENSSSCP00000037223.2, ENSSSCT00000065893.3
    Conserved Domains (1) summary
    smart00092
    Location:26 → 142
    RNAse_Pc; Pancreatic ribonuclease

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010449.5 Reference Sscrofa11.1 Primary Assembly

    Range
    78249479..78262846 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021098367.1 → XP_020954026.1  angiogenin isoform X1

    UniProtKB/TrEMBL
    A0A4X1UVR5
    Conserved Domains (1) summary
    smart00092
    Location:81 → 197
    RNAse_Pc; Pancreatic ribonuclease
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P31346.1 GenPept UniProtKB/Swiss-Prot:P31346

Gene LinkOut

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