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SLC11A2 solute carrier family 11 member 2 [ Sus scrofa (pig) ]

Gene ID: 733595, updated on 17-Aug-2024

Summary

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Official Symbol
SLC11A2provided by VGNC
Official Full Name
solute carrier family 11 member 2provided by VGNC
Primary source
VGNC:VGNC:92920
See related
Ensembl:ENSSSCG00000034039
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
DMT1
Expression
Ubiquitous expression in kidney (RPKM 5.0), liver (RPKM 4.8) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See SLC11A2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) Unplaced Scaffold NW_018085018.1 (341375..380525)

NW_018085018.1Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P1 pseudogene Neighboring gene transcription factor CP2 Neighboring gene cysteine and serine rich nuclear protein 2 Neighboring gene LETM1 domain containing 1 Neighboring gene HIG1 hypoxia inducible domain family member 1C Neighboring gene thiol methyltransferase 1A

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018085018 Unplaced Scaffold Reference Sscrofa11.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Maternal protein restriction depresses the duodenal expression of iron transporters and serum iron level in male weaning piglets. Ma W, et al. Br J Nutr, 2017 Apr. PMID 28534724
  2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cadmium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables manganese ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in metal ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
natural resistance-associated macrophage protein 2
Names
divalent metal transporter 1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128440.1 → NP_001121912.1  natural resistance-associated macrophage protein 2

    See identical proteins and their annotated locations for NP_001121912.1

    Status: PROVISIONAL

    Source sequence(s)
    EU647217
    UniProtKB/TrEMBL
    A0A0B8S011, A0A480HUS9, A0A8D1KQR9, A0A8D1YU94, B2ZDZ3
    Related
    ENSSSCP00000057157.3, ENSSSCT00000042375.3
    Conserved Domains (2) summary
    TIGR01197
    Location:69 → 468
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
    pfam01566
    Location:91 → 474
    Nramp; Natural resistance-associated macrophage protein

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NW_018085018.1 Reference Sscrofa11.1 Primary Assembly

    Range
    341375..380525
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021081706.1 → XP_020937365.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8D1D5S2, A0A8D1GL51
    Conserved Domains (1) summary
    TIGR01197
    Location:96 → 495
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  2. XM_021081710.1 → XP_020937369.1  natural resistance-associated macrophage protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A4X1WCJ1, A0A5G2QXA1, A0A8D0ILB9, A0A8D0WPW7
    Conserved Domains (1) summary
    TIGR01197
    Location:69 → 468
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  3. XM_021081709.1 → XP_020937368.1  natural resistance-associated macrophage protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A4X1WCJ1, A0A5G2QXA1, A0A8D0ILB9, A0A8D0WPW7
    Related
    ENSSSCP00000069564.2, ENSSSCT00000080368.2
    Conserved Domains (1) summary
    TIGR01197
    Location:69 → 468
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  4. XM_021081708.1 → XP_020937367.1  natural resistance-associated macrophage protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A4X1WCJ1, A0A5G2QXA1, A0A8D0ILB9, A0A8D0WPW7
    Related
    ENSSSCP00000057340.3, ENSSSCT00000047355.3
    Conserved Domains (1) summary
    TIGR01197
    Location:69 → 468
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  5. XM_021081707.1 → XP_020937366.1  natural resistance-associated macrophage protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8D0WWI2, A0A8D1D5S6
    Conserved Domains (1) summary
    TIGR01197
    Location:83 → 482
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
Nucleotide Protein
Heading Accession and Version

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