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eEF2 eukaryotic translation elongation factor 2 [ Bombyx mori (domestic silkworm) ]

Gene ID: 733027, updated on 16-May-2024

Summary

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Gene symbol
eEF2
Gene description
eukaryotic translation elongation factor 2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bombyx mori
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea; Bombycidae; Bombycinae; Bombyx
Also known as
tef2
Orthologs
fruit fly all
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Genomic context

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See eEF2 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_01 current ASM3026992v2 (GCF_030269925.1) 19 NC_085125.1 (13064289..13074444, complement)
103 previous assembly Bmori_2016v1.0 (GCF_014905235.1) 19 NC_051376.1 (12844556..12854711, complement)

Chromosome 19 - NC_085125.1Genomic Context describing neighboring genes Neighboring gene retinal-specific phospholipid-transporting ATPase ABCA4 Neighboring gene cytidine/uridine monophosphate kinase Dak1 Neighboring gene microRNA mir-2738 Neighboring gene uncharacterized LOC134200703 Neighboring gene uncharacterized LOC134200705 Neighboring gene transcription factor JunD

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. [Protein databank for several tissues derived from five instar of silkworm]. Zhong BX. Yi Chuan Xue Bao, 2001. PMID 11280994
  2. Large scale full-length cDNA sequencing reveals a unique genomic landscape in a lepidopteran model insect, Bombyx mori. Suetsugu Y, et al. G3 (Bethesda), 2013 Sep 4. PMID 23821615, Free PMC Article
  3. Transcriptomic analysis of developmental features of Bombyx mori wing disc during metamorphosis. Ou J, et al. BMC Genomics, 2014 Sep 27. PMID 25261999, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ribosome binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in translational elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
translation elongation factor 2
Names
EF-2
elongation factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044128.2 → NP_001037593.1  translation elongation factor 2 isoform 1

    See identical proteins and their annotated locations for NP_001037593.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ515926
    UniProtKB/TrEMBL
    A0A8R1TAW0
    Conserved Domains (6) summary
    cd01885
    Location:40 → 256
    EF2; Elongation Factor 2 (EF2) in archaea and eukarya
    cd01681
    Location:580 → 752
    aeEF2_snRNP_like_IV; This family represents domain IV of archaeal and eukaryotic elongation factor 2 (aeEF-2) and of an evolutionarily conserved U5 snRNP-specific protein. U5 snRNP is a GTP-binding factor closely related to the ribosomal translocase EF-2. In complex with GTP, ...
    cd04096
    Location:748 → 827
    eEF2_snRNP_like_C; eEF2_snRNP_like_C: this family represents a C-terminal domain of eukaryotic elongation factor 2 (eEF-2) and a homologous domain of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116 kD) and, its yeast counterpart ...
    PTZ00416
    Location:22 → 864
    PTZ00416; elongation factor 2; Provisional
    cd03700
    Location:400 → 494
    EF2_snRNP_like_II; Domain II of elongation factor 2 and C-terminal domain of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein
    cd16261
    Location:509 → 580
    EF2_snRNP_III; Domain III of Elongation Factor 2 (EF2)

  2. NM_001170394.1 → NP_001163865.1  translation elongation factor 2 isoform 2

    See identical proteins and their annotated locations for NP_001163865.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ443396
    UniProtKB/Swiss-Prot
    P82216, Q19P05, Q1HPK6
    UniProtKB/TrEMBL
    F8SKB6
    Conserved Domains (1) summary
    PTZ00416
    Location:1 → 844
    PTZ00416; elongation factor 2; Provisional

RefSeqs of Annotated Genomes: GCF_030269925.1-RS_2024_01

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM3026992v2 Primary Assembly

Genomic

  1. NC_085125.1 Reference ASM3026992v2 Primary Assembly

    Range
    13064289..13074444 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_062673827.1 → XP_062529811.1  translation elongation factor 2 isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q1HPK6.1 GenPept UniProtKB/Swiss-Prot:Q1HPK6

Gene LinkOut

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