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GAGE12J G antigen 12J [ Homo sapiens (human) ]

Gene ID: 729396, updated on 10-Oct-2023

Summary

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Official Symbol
GAGE12Jprovided by HGNC
Official Full Name
G antigen 12Jprovided by HGNC
Primary source
HGNC:HGNC:17778
See related
Ensembl:ENSG00000224659 MIM:300733; AllianceGenome:HGNC:17778
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GAGE11
Expression
Restricted expression toward testis (RPKM 116.9) See more
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Genomic context

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Location:
Xp11.23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (49322037..49329384)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (48733900..48741226)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (49178516..49185863)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20845 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:49133671-49134170 Neighboring gene protein phosphatase 1 regulatory subunit 3F Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29638 Neighboring gene uncharacterized LOC124905188 Neighboring gene G antigen 10 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:49216999-49217663 Neighboring gene G antigen 13 Neighboring gene G antigen 12B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. Gjerstorff MF, et al. Tissue Antigens, 2008 Mar. PMID 18179644
  2. A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220. Hou P, et al. Cancer Res, 2017 Aug 15. PMID 28625976, Free PMC Article
  3. Creation of genome-wide protein expression libraries using random activation of gene expression. Harrington JJ, et al. Nat Biotechnol, 2001 May. PMID 11329013
  4. The DNA sequence of the human X chromosome. Ross MT, et al. Nature, 2005 Mar 17. PMID 15772651, Free PMC Article
  5. A reference map of the human binary protein interactome. Luck K, et al. Nature, 2020 Apr. PMID 32296183, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
G antigen 12J
Names
G antigen 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098406.4 → NP_001091876.2  G antigen 12J

    Status: VALIDATED

    Source sequence(s)
    AC233302
    Consensus CDS
    CCDS43939.1
    UniProtKB/Swiss-Prot
    A6NER3
    UniProtKB/TrEMBL
    B7ZVY3
    Related
    ENSP00000409832.2, ENST00000442437.3
    Conserved Domains (1) summary
    pfam05831
    Location:1 → 114
    GAGE; GAGE protein

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    49322037..49329384
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    48733900..48741226
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A6NER3.2 GenPept UniProtKB/Swiss-Prot:A6NER3

Gene LinkOut

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